Value of echocardiographic measurement of left ventricular mass in predicting cardiovascular morbid events in hypertensive men

P. N. Casale, R. B. Devereux, M. Milner, G. Zullo, Gregory A Harshfield, T. G. Pickering, J. H. Laragh

Research output: Contribution to journalArticle

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Abstract

To assess whether echocardiographic and electrocardiographic detection of left ventricular hypertrophy could predict cardiovascular morbid events in patients with uncomplicated essential hypertension, we followed 140 men for a mean of 4.8 years. Initial echocardiographic measurements of left ventricular mass were normal (<125 g/m2 body surface area) in 111 patients and revealed hypertrophy in 29 patients. Morbid events occurred in more patients with hypertrophy on echocardiography (7 of 29, 4.6/100 patient-years) than with normal ventricular mass (7 of 111, 1.4/100 patient-years; p < 0.01). Electrocardiography showed hypertrophy in too few patients to be of predictive value. Multiple logistic regression analysis showed that left ventricular mass index had the highest independent relative risk for future events and that systolic and diastolic pressures and age had slightly lower relative risks. In men with mild uncomplicated hypertension, left ventricular hypertrophy detected by echocardiography identifies patients at high risk for cardiovascular morbid events and is a significant risk factor for future morbid events independent of age, blood pressure, or resting ventricular function.

Original languageEnglish (US)
Pages (from-to)173-178
Number of pages6
JournalAnnals of internal medicine
Volume105
Issue number2
DOIs
StatePublished - Jan 1 1986

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Hypertrophy
Left Ventricular Hypertrophy
Blood Pressure
Echocardiography
Ventricular Function
Body Surface Area
Electrocardiography
Logistic Models
Regression Analysis
Hypertension
Essential Hypertension

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Value of echocardiographic measurement of left ventricular mass in predicting cardiovascular morbid events in hypertensive men. / Casale, P. N.; Devereux, R. B.; Milner, M.; Zullo, G.; Harshfield, Gregory A; Pickering, T. G.; Laragh, J. H.

In: Annals of internal medicine, Vol. 105, No. 2, 01.01.1986, p. 173-178.

Research output: Contribution to journalArticle

Casale, P. N. ; Devereux, R. B. ; Milner, M. ; Zullo, G. ; Harshfield, Gregory A ; Pickering, T. G. ; Laragh, J. H. / Value of echocardiographic measurement of left ventricular mass in predicting cardiovascular morbid events in hypertensive men. In: Annals of internal medicine. 1986 ; Vol. 105, No. 2. pp. 173-178.
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