Variation in dialysis facility referral for kidney transplantation among patients with end-stage renal disease in Georgia

Rachel E. Patzer, Laura C. Plantinga, Sudeshna Paul, Jennifer Gander, Jenna Krisher, Leighann Sauls, Eric M. Gibney, Laura L Mulloy, Stephen O. Pastan

Research output: Contribution to journalArticle

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Abstract

Importance: Dialysis facilities in the United States are required to educate patients with end-stage renal disease about all treatment options, including kidney transplantation. Patients receiving dialysis typically require a referral for kidney transplant evaluation at a transplant center from a dialysis facility to start the transplantation process, but the proportion of patients referred for transplantation is unknown. Objective: To describe variation in dialysis facility-level referral for kidney transplant evaluation and factors associated with referral among patients initiating dialysis in Georgia, the US state with the lowest kidney transplantation rates. Design, Setting, and Participants: Examination of United States Renal Data System data from a cohort of 15 279 incident, adult (18-69 years) patients with end-stage renal disease from 308 Georgia dialysis facilities from January 2005 to September 2011, followed up through September 2012, linked to kidney transplant referral data collected from adult transplant centers in Georgia in the same period. Main Outcomes and Measures: Referral for kidney transplant evaluation within 1 year of starting dialysis at any of the 3 Georgia transplant centers was the primary outcome; placement on the deceased donor waiting list was also examined. Results: The median within-facility percentage of patients referred within 1 year of starting dialysis was 24.4%(interquartile range, 16.7%-33.3%) and varied from 0% to 75.0%. Facilities in the lowest tertile of referral (<19.2%) were more likely to treat patients living in high-poverty neighborhoods (absolute difference, 21.8%[95%CI, 14.1%-29.4%]), had a higher patient to social worker ratio (difference, 22.5 [95%CI, 9.7-35.2]), and were more likely nonprofit (difference, 17.6%[95%CI, 7.7%-27.4%]) compared with facilities in the highest tertile of referral (>31.3%). In multivariable, multilevel analyses, factors associated with lower referral for transplantation, such as older age, white race, and nonprofit facility status, were not always consistent with the factors associated with lower waitlisting. Conclusions and Relevance: In Georgia overall, a limited proportion of patients treated with dialysis were referred for kidney transplant evaluation between 2005 and 2011, but there was substantial variability in referral among facilities. Variables associated with referral were not always associated with waitlisting, suggesting that different factors may account for disparities in referral.

Original languageEnglish (US)
Pages (from-to)582-594
Number of pages13
JournalJAMA - Journal of the American Medical Association
Volume314
Issue number6
DOIs
StatePublished - Aug 11 2015

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Kidney Transplantation
Chronic Kidney Failure
Dialysis
Referral and Consultation
Transplants
Kidney
Transplantation
Multilevel Analysis
Waiting Lists
Information Systems
Outcome Assessment (Health Care)
Tissue Donors

ASJC Scopus subject areas

  • Medicine(all)

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Variation in dialysis facility referral for kidney transplantation among patients with end-stage renal disease in Georgia. / Patzer, Rachel E.; Plantinga, Laura C.; Paul, Sudeshna; Gander, Jennifer; Krisher, Jenna; Sauls, Leighann; Gibney, Eric M.; Mulloy, Laura L; Pastan, Stephen O.

In: JAMA - Journal of the American Medical Association, Vol. 314, No. 6, 11.08.2015, p. 582-594.

Research output: Contribution to journalArticle

Patzer, Rachel E. ; Plantinga, Laura C. ; Paul, Sudeshna ; Gander, Jennifer ; Krisher, Jenna ; Sauls, Leighann ; Gibney, Eric M. ; Mulloy, Laura L ; Pastan, Stephen O. / Variation in dialysis facility referral for kidney transplantation among patients with end-stage renal disease in Georgia. In: JAMA - Journal of the American Medical Association. 2015 ; Vol. 314, No. 6. pp. 582-594.
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abstract = "Importance: Dialysis facilities in the United States are required to educate patients with end-stage renal disease about all treatment options, including kidney transplantation. Patients receiving dialysis typically require a referral for kidney transplant evaluation at a transplant center from a dialysis facility to start the transplantation process, but the proportion of patients referred for transplantation is unknown. Objective: To describe variation in dialysis facility-level referral for kidney transplant evaluation and factors associated with referral among patients initiating dialysis in Georgia, the US state with the lowest kidney transplantation rates. Design, Setting, and Participants: Examination of United States Renal Data System data from a cohort of 15 279 incident, adult (18-69 years) patients with end-stage renal disease from 308 Georgia dialysis facilities from January 2005 to September 2011, followed up through September 2012, linked to kidney transplant referral data collected from adult transplant centers in Georgia in the same period. Main Outcomes and Measures: Referral for kidney transplant evaluation within 1 year of starting dialysis at any of the 3 Georgia transplant centers was the primary outcome; placement on the deceased donor waiting list was also examined. Results: The median within-facility percentage of patients referred within 1 year of starting dialysis was 24.4{\%}(interquartile range, 16.7{\%}-33.3{\%}) and varied from 0{\%} to 75.0{\%}. Facilities in the lowest tertile of referral (<19.2{\%}) were more likely to treat patients living in high-poverty neighborhoods (absolute difference, 21.8{\%}[95{\%}CI, 14.1{\%}-29.4{\%}]), had a higher patient to social worker ratio (difference, 22.5 [95{\%}CI, 9.7-35.2]), and were more likely nonprofit (difference, 17.6{\%}[95{\%}CI, 7.7{\%}-27.4{\%}]) compared with facilities in the highest tertile of referral (>31.3{\%}). In multivariable, multilevel analyses, factors associated with lower referral for transplantation, such as older age, white race, and nonprofit facility status, were not always consistent with the factors associated with lower waitlisting. Conclusions and Relevance: In Georgia overall, a limited proportion of patients treated with dialysis were referred for kidney transplant evaluation between 2005 and 2011, but there was substantial variability in referral among facilities. Variables associated with referral were not always associated with waitlisting, suggesting that different factors may account for disparities in referral.",
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AU - Krisher, Jenna

AU - Sauls, Leighann

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N2 - Importance: Dialysis facilities in the United States are required to educate patients with end-stage renal disease about all treatment options, including kidney transplantation. Patients receiving dialysis typically require a referral for kidney transplant evaluation at a transplant center from a dialysis facility to start the transplantation process, but the proportion of patients referred for transplantation is unknown. Objective: To describe variation in dialysis facility-level referral for kidney transplant evaluation and factors associated with referral among patients initiating dialysis in Georgia, the US state with the lowest kidney transplantation rates. Design, Setting, and Participants: Examination of United States Renal Data System data from a cohort of 15 279 incident, adult (18-69 years) patients with end-stage renal disease from 308 Georgia dialysis facilities from January 2005 to September 2011, followed up through September 2012, linked to kidney transplant referral data collected from adult transplant centers in Georgia in the same period. Main Outcomes and Measures: Referral for kidney transplant evaluation within 1 year of starting dialysis at any of the 3 Georgia transplant centers was the primary outcome; placement on the deceased donor waiting list was also examined. Results: The median within-facility percentage of patients referred within 1 year of starting dialysis was 24.4%(interquartile range, 16.7%-33.3%) and varied from 0% to 75.0%. Facilities in the lowest tertile of referral (<19.2%) were more likely to treat patients living in high-poverty neighborhoods (absolute difference, 21.8%[95%CI, 14.1%-29.4%]), had a higher patient to social worker ratio (difference, 22.5 [95%CI, 9.7-35.2]), and were more likely nonprofit (difference, 17.6%[95%CI, 7.7%-27.4%]) compared with facilities in the highest tertile of referral (>31.3%). In multivariable, multilevel analyses, factors associated with lower referral for transplantation, such as older age, white race, and nonprofit facility status, were not always consistent with the factors associated with lower waitlisting. Conclusions and Relevance: In Georgia overall, a limited proportion of patients treated with dialysis were referred for kidney transplant evaluation between 2005 and 2011, but there was substantial variability in referral among facilities. Variables associated with referral were not always associated with waitlisting, suggesting that different factors may account for disparities in referral.

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