Vascular reactivity in hypertension: Altered effect of ouabain

R. C. Webb, D. F. Bohr

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

Ouabain inhibits the relaxing effect of Ca2+ (but not of Mn2+) on contractile responses in tail artery strips isolated from spontaneously hypertensive and normotensive rats. The magnitude of ouabain inhibition was greater in vascular strips from hypertensive rats suggesting a significant difference in basic membrane function in hypertensive vascular smooth muscle.

Original languageEnglish (US)
Pages (from-to)220-222
Number of pages3
JournalExperientia
Volume36
Issue number2
DOIs
StatePublished - Feb 1980
Externally publishedYes

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology

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