Velocity-coded colour magnetic resonance angiography and perfusion-weighted magnetic resonance imaging for the evaluation of extracranial-to-intracranial arterial bypass surgery

Nobuhiko Miyazawa, Shigeki Aoki, Keiji Toyama, Ali Syed Arbab, Masaaki Hori, Takako Umeda, Tsutomu Araki, Hideaki Nukui

Research output: Contribution to journalArticle

Abstract

Background and purpose: Velocity-coded colour magnetic resonance angiography (VCCMRA) and perfusion magnetic resonance imaging (pMRI) were evaluated as methods for investigating the efficacy of extracranial-to-intracranial arterial bypass (EC-IC bypass) by comparing the findings of VCCMRA and those of cerebral angiography and by measuring the improvement ratio after EC-IC bypass by pMRI compared to that by single photon emission computed tomography (SPECT) using the autoradiographic technique. Methods: Thirteen patients who underwent VCCMRA, angiography, SPECT, and pMRI before and after surgery were analyzed. Findings of VCCMRA were compared to those of angiography. Improvement ratio was calculated compared to the cerebellum for cerebral blood volume, mean transit time (MTT), and regional cerebral blood flow (rCBF) as measured by pMRI and quantitative SPECT. Results: Findings of VCCMRA were in good agreement with those of angiography and clearly showed the direction of bypass flow. No statistically significant correlation was observed between the improvement ratios in CBF in the hemisphere and middle cerebral artery territory on the surgical and non-surgical sides and in rCBF in the same regions of interest (ROIs) (r=-0.574, 0.09). However, a statistically significant correlation was observed between the cerebrovascular reserve capacity (CVRC) in the hemisphere on the surgical side and in MTT in the same ROIs (r=0.955, P<0.001). Conclusion: VCCMRA may clearly show the direction of flow in the EC-IC bypass. MIT measured by pMRI may indicate the postoperative state of CVRC. These techniques could replace angiography and positron emission tomography or SPECT in patients undergoing EC-IC bypass.

Original languageEnglish (US)
Pages (from-to)48-59
Number of pages12
JournalClinical Neurology and Neurosurgery
Volume105
Issue number1
DOIs
StatePublished - Dec 1 2002
Externally publishedYes

Fingerprint

Cerebral Revascularization
Magnetic Resonance Angiography
Color
Single-Photon Emission-Computed Tomography
Cerebrovascular Circulation
Angiography
Regional Blood Flow
Cerebral Angiography
Middle Cerebral Artery
Positron-Emission Tomography
Cerebellum

Keywords

  • Extracranial-to-intracranial arterial bypass
  • Major artery occlusion
  • Perfusion-weighted magnetic resonance imaging
  • Phase contrast magnetic resonance imaging
  • Single photon emission computed tomography

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Cite this

Velocity-coded colour magnetic resonance angiography and perfusion-weighted magnetic resonance imaging for the evaluation of extracranial-to-intracranial arterial bypass surgery. / Miyazawa, Nobuhiko; Aoki, Shigeki; Toyama, Keiji; Arbab, Ali Syed; Hori, Masaaki; Umeda, Takako; Araki, Tsutomu; Nukui, Hideaki.

In: Clinical Neurology and Neurosurgery, Vol. 105, No. 1, 01.12.2002, p. 48-59.

Research output: Contribution to journalArticle

Miyazawa, Nobuhiko ; Aoki, Shigeki ; Toyama, Keiji ; Arbab, Ali Syed ; Hori, Masaaki ; Umeda, Takako ; Araki, Tsutomu ; Nukui, Hideaki. / Velocity-coded colour magnetic resonance angiography and perfusion-weighted magnetic resonance imaging for the evaluation of extracranial-to-intracranial arterial bypass surgery. In: Clinical Neurology and Neurosurgery. 2002 ; Vol. 105, No. 1. pp. 48-59.
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AU - Miyazawa, Nobuhiko

AU - Aoki, Shigeki

AU - Toyama, Keiji

AU - Arbab, Ali Syed

AU - Hori, Masaaki

AU - Umeda, Takako

AU - Araki, Tsutomu

AU - Nukui, Hideaki

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AB - Background and purpose: Velocity-coded colour magnetic resonance angiography (VCCMRA) and perfusion magnetic resonance imaging (pMRI) were evaluated as methods for investigating the efficacy of extracranial-to-intracranial arterial bypass (EC-IC bypass) by comparing the findings of VCCMRA and those of cerebral angiography and by measuring the improvement ratio after EC-IC bypass by pMRI compared to that by single photon emission computed tomography (SPECT) using the autoradiographic technique. Methods: Thirteen patients who underwent VCCMRA, angiography, SPECT, and pMRI before and after surgery were analyzed. Findings of VCCMRA were compared to those of angiography. Improvement ratio was calculated compared to the cerebellum for cerebral blood volume, mean transit time (MTT), and regional cerebral blood flow (rCBF) as measured by pMRI and quantitative SPECT. Results: Findings of VCCMRA were in good agreement with those of angiography and clearly showed the direction of bypass flow. No statistically significant correlation was observed between the improvement ratios in CBF in the hemisphere and middle cerebral artery territory on the surgical and non-surgical sides and in rCBF in the same regions of interest (ROIs) (r=-0.574, 0.09). However, a statistically significant correlation was observed between the cerebrovascular reserve capacity (CVRC) in the hemisphere on the surgical side and in MTT in the same ROIs (r=0.955, P<0.001). Conclusion: VCCMRA may clearly show the direction of flow in the EC-IC bypass. MIT measured by pMRI may indicate the postoperative state of CVRC. These techniques could replace angiography and positron emission tomography or SPECT in patients undergoing EC-IC bypass.

KW - Extracranial-to-intracranial arterial bypass

KW - Major artery occlusion

KW - Perfusion-weighted magnetic resonance imaging

KW - Phase contrast magnetic resonance imaging

KW - Single photon emission computed tomography

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