Viloxazine in the treatment of depressive neurosis: A placebo and standard (imipramine) controlled clinical study

W. M. Petrie, J. P. McEvoy, W. H. Wilson, T. A. Ban, W. Guy

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Abstract

In a 4-week double-blind trial, 33 patients with depressive neurosis were randomly assigned to either viloxazine, imipramine or placebo. Statistically significant improvement was observed in all treatment groups. Imipramine exhibited significant improvement earlier in depressive symptoms, while viloxazine showed significant improvement earlier in anxious symptoms. The same frequency of treatment emergent symptoms occurred in the treatment groups. Premature termination as a consequence of adverse reactions was required in only 1 viloxazine and 1 placebo patient.

Original languageEnglish (US)
Pages (from-to)193-196
Number of pages4
JournalUnknown Journal
Volume15
Issue number3
DOIs
Publication statusPublished - Jan 1 1980
Externally publishedYes

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ASJC Scopus subject areas

  • Medicine(all)

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