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Betty Sue Pace

Professor

 https://orcid.org/0000-0002-1275-4112
  • 1490 Citations
  • 23 h-Index
1988 …2019
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  • 8 Similar Profiles
Globins Medicine & Life Sciences
Fetal Hemoglobin Medicine & Life Sciences
Sickle Cell Anemia Medicine & Life Sciences
Genes Chemical Compounds
Erythroid Cells Medicine & Life Sciences
Hydroxyurea Medicine & Life Sciences
Gene Expression Medicine & Life Sciences
Butyrates Medicine & Life Sciences

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Projects 1988 2018

PRIDE-Functional and Applied Genomics of Blood Disorders

Pace, B. S.

Project: Research project

Genome-wide Association Study: Fetal Hemoglobin Phenotypes in Sickle Cell Disease

Pace, B. S.

National Institutes of Health

4/1/09 → 3/31/11

Project: Research project

Fetal Hemoglobin
Genome-Wide Association Study
Sickle Cell Anemia
Exercise
Phenotype

Sickle Cell Disease Research Center (SCDRC) Summer Institute/Mentoring Program

Pace, B. S.

National Institutes of Health

9/15/06 → 6/30/11

Project: Research project

Sickle Cell Anemia
Research
Biomedical Research
Mentoring
Public Health

Mechanisms for Stat 3-Mediated Gamma-Globin Gene Silenc*

Pace, B. S.

National Institutes of Health

4/11/03 → 3/31/08

Project: Research project

gamma-Globins
Genes
Sickle Cell Anemia
Gene Silencing
STAT3 Transcription Factor

Mechanisms For p38 MAP Kinase Dependent Gene Induction

Pace, B. S.

National Institutes of Health

9/30/01 → 5/31/18

Project: Research project

Globins
Histone Deacetylase Inhibitors
gamma-Globins
Sickle Cell Anemia
p38 Mitogen-Activated Protein Kinases

Research Output 1994 2019

1 Citation (Scopus)

Conjugate prodrug AN-233 induces fetal hemoglobin expression in sickle erythroid progenitors and β-YAC transgenic mice

Oseghale, A. R., Zhu, X., Li, B., Peterson, K. R., Nudelman, A., Rephaeli, A., Xu, H. & Pace, B. S., Nov 1 2019, In : Blood Cells, Molecules, and Diseases. 79, 102345.

Research output: Contribution to journal › Article

Fetal Hemoglobin
Globins
Prodrugs
Transgenic Mice
Sickle Cell Anemia
2 Citations (Scopus)

Mechanisms of NRF2 activation to mediate fetal hemoglobin induction and protection against oxidative stress in sickle cell disease

Zhu, X., Oseghale, A. R., Nicole, L. H., Li, B. & Pace, B. S., Feb 1 2019, In : Experimental Biology and Medicine. 244, 2, p. 171-182 12 p.

Research output: Contribution to journal › Review article

Fetal Hemoglobin
Oxidative stress
Sickle Cell Anemia
Oxidative Stress
Sickle Hemoglobin
8 Citations (Scopus)

MIR-144-mediated NRF2 gene silencing inhibits fetal hemoglobin expression in sickle cell disease

Li, B., Zhu, X., Ward, C. M., Starlard-Davenport, A., Takezaki, M., Berry, A., Ward, A., Wilder, C., Neunert, C., Kutlar, A. & Pace, B. S., Feb 2019, In : Experimental Hematology. 70, p. 85-96.e5

Research output: Contribution to journal › Article

Fetal Hemoglobin
Globins
Sickle Cell Anemia
Gene Silencing
MicroRNAs
1 Citation (Scopus)

MIR29B mediates epigenetic mechanisms of HBG gene activation

Starlard-Davenport, A., Smith, A., Vu, L., Li, B. & Pace, B. S., Jul 2019, In : British Journal of Haematology. 186, 1, p. 91-100 10 p.

Research output: Contribution to journal › Article

Sickle Cell Anemia
Epigenomics
Transcriptional Activation
Methyltransferases
Cytidine Deaminase
3 Citations (Scopus)

Fetal hemoglobin induction in sickle erythroid progenitors using a synthetic zinc finger DNA-binding domain

Li, B., Zhu, X., Hossain, M. A., Guy, C. R., Xu, H., Bungert, J. & Pace, B. S., Aug 31 2018, In : Haematologica. 103, 9, p. e384-e387

Research output: Contribution to journal › Letter

Fetal Hemoglobin
Zinc Fingers
DNA