Clive A. Slaughter

Professor

  • 22175 Citations
  • 67 h-Index
1975 …2019

Research output per year

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Research Output

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1998

Molecular characterization of the 50- and 57-kDa subunits of the bovine vacuolar proton pump

Zhou, Z., Peng, S. B., Crider, B. P., Slaughter, C. A., Xie, X. S. & Stone, D. K., Mar 6 1998, In : Journal of Biological Chemistry. 273, 10, p. 5878-5884 7 p.

Research output: Contribution to journalArticle

31 Scopus citations

Structure and expression of the FlaA periplasmic flagellar protein of Borrelia burgdorferi

Ge, Y., Li, C., Corum, L., Slaughter, C. A. & Charon, N. W., May 1 1998, In : Journal of Bacteriology. 180, 9, p. 2418-2425 8 p.

Research output: Contribution to journalArticle

61 Scopus citations

The specificity of peptides bound to human histocompatibility leukocyte antigen (HLA)-B27 influences the prevalence of arthritis in HLA-B27 transgenic rats

Zhou, B. M., Sayad, A., Simmons, W. A., Jones, R. C., Maika, S. D., Satumtira, N., Dorris, M. L., Gaskell, S. J., Bordoli, R. S., Sartor, R. B., Slaughter, C. A., Richardson, J. A., Hammer, R. E. & Taurog, J. D., Sep 7 1998, In : Journal of Experimental Medicine. 188, 5, p. 877-886 10 p.

Research output: Contribution to journalArticle

45 Scopus citations

Transmembrane domain of cystic fibrosis transmembrane conductance regulator: Design, characterization, and secondary structure of synthetic peptides ml-m6

Wigley, W. C., Vijayakumar, S., Jones, J. D., Slaughter, C. A. & Thomas, P. J., Jan 20 1998, In : Biochemistry. 37, 3, p. 844-853 10 p.

Research output: Contribution to journalArticle

37 Scopus citations
1997

Active site-directed inhibitors of Rhodococcus 20 S proteasome. Kinetics and mechanism

Mc Cormack, T., Baumeister, W., Grenier, L., Moomaw, C., Plamondon, L., Pramanik, B., Slaughter, C. A., Soucy, F., Stein, R., Zühl, F. & Dick, L., Oct 17 1997, In : Journal of Biological Chemistry. 272, 42, p. 26103-26109 7 p.

Research output: Contribution to journalArticle

57 Scopus citations

A new MHC locus that influences class I peptide presentation

Simmons, W. A., Roopenian, D. C., Summerfield, S. G., Jones, R. C., Galocha, B., Christianson, G. J., Maika, S. D., Zhou, M., Gaskell, S. J., Bordoli, R. S., Ploegh, H. L., Slaughter, C. A., Lindahl, K. F., Hammer, R. E. & Taurog, J. D., Jan 1 1997, In : Immunity. 7, 5, p. 641-651 11 p.

Research output: Contribution to journalArticle

11 Scopus citations

cDNA cloning and functional analysis of p44.5 and p55, two regulatory subunits of the 26S proteasome

Saito, A., Watanabe, T. K., Shimada, Y., Fujiwara, T., Slaughter, C. A., Demartino, G. N., Tanahashi, N. & Tanaka, K., Dec 12 1997, In : Gene. 203, 2, p. 241-250 10 p.

Research output: Contribution to journalArticle

22 Scopus citations

Cytochrome c(y) of Rhodobacter capsulatus is attached to the cytoplasmic membrane by an uncleaved signal sequence-like anchor

Myllykallio, H., Jenney, F. E., Moomaw, C. R., Slaughter, C. A. & Daldal, F., Jan 1 1997, In : Journal of Bacteriology. 179, 8, p. 2623-2631 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

Liu, X., Zou, H., Slaughter, C. & Wang, X., Apr 18 1997, In : Cell. 89, 2, p. 175-184 10 p.

Research output: Contribution to journalArticle

1548 Scopus citations

Human succinic semialdeyde dehydrogenase: Molecular cloning and chromosomal localization

Trettel, F., Malaspina, P., Jodice, C., Novelletto, A., Slaughter, C. A., Caudle, D. L., Hinson, D. D., Chambliss, K. L. & Gibson, K. M., Apr 1 1997, In : Advances in experimental medicine and biology. 414, p. 253-260 8 p.

Research output: Contribution to journalArticle

33 Scopus citations

Molecular properties of the proteasome activator PA28 family proteins and γ-interferon regulation

Tanahashi, N., Yokota, K. Y., Ahn, J. Y., Chung, C. H., Fujiwara, T., Takahashi, E. I., DeMartino, G. N., Slaughter, C. A., Toyonaga, T., Yamamura, K. I., Shimbara, N. & Tanaka, K., Jan 1 1997, In : Genes to Cells. 2, 3, p. 195-211 17 p.

Research output: Contribution to journalArticle

107 Scopus citations

Novel HY peptide antigens presented by HLA-B271

Simmons, W. A., Summerfield, S. G., Roopenian, D. C., Slaughter, C. A., Zuberi, A. R., Gaskell, S. J., Bordoli, R. S., Hoyes, J., Moomaw, C. R., Colbert, R. A., Leong, L. Y. W., Butcher, G. W., Hammer, R. E. & Taurog, J. D., Dec 1 1997, In : Journal of Immunology. 159, 6, p. 2750-2759 10 p.

Research output: Contribution to journalArticle

26 Scopus citations

Relative functions of the α and β subunits of the proteasome activator, PA28

Song, X., Von Kampen, J., Slaughter, C. A. & DeMartino, G. N., Oct 31 1997, In : Journal of Biological Chemistry. 272, 44, p. 27994-28000 7 p.

Research output: Contribution to journalArticle

64 Scopus citations

Structural and functional effects of PA700 and modulator protein on proteasomes

Adams, G. M., Falke, S., Goldberg, A. L., Slaughter, C. A., DeMartino, G. N. & Gogol, E. P., Oct 31 1997, In : Journal of Molecular Biology. 273, 3, p. 646-657 12 p.

Research output: Contribution to journalArticle

57 Scopus citations

Yeast counterparts of subunits S5a and p58 (S3) of the human 26S proteasome are encoded by two multicopy suppressors of nin1-1

Kominami, K. I., Okura, N., Kawamura, M., DeMartino, G. N., Slaughter, C. A., Shimbara, N., Chung, C. H., Fujimuro, M., Yokosawa, H., Shimizu, Y., Tanahashi, N., Tanaka, K. & Toh-e, A., Jan 1997, In : Molecular Biology of the Cell. 8, 1, p. 171-187 17 p.

Research output: Contribution to journalArticle

87 Scopus citations
1996

Absence of γ-sarcoglycan (35 DAG) in autosomal recessive muscular dystrophy linked to chromosome 13q12

Jung, D., Leturcq, F., Sunada, Y., Duclos, F., Tomé, F. M. S., Moomaw, C., Merlini, L., Azibi, K., Chaouch, M., Slaughter, C. A., Fardeau, M., Kaplan, J. C. & Campbell, K. P., Feb 26 1996, In : FEBS Letters. 381, 1-2, p. 15-20 6 p.

Research output: Contribution to journalArticle

52 Scopus citations

A model for the quaternary structure of the proteasome activator PA28

Song, X., Mott, J. D., Von Kampen, J., Pramanik, B., Tanaka, K., Slaughter, C. A. & DeMartino, G. N., Oct 30 1996, In : Journal of Biological Chemistry. 271, 42, p. 26410-26417 8 p.

Research output: Contribution to journalArticle

66 Scopus citations

cDNA cloning and functional analysis of the p97 subunit of the 265 proteasome, a polypeptide identical to the type-1 tumor-necrosis-factor-receptor-associated protein-2/55.11

Tsurumi, C., Shimizu, Y., Saeki, M., Kato, S., Demartino, G. N., Slaughter, C. A., Fujimuro, M., Yokosawa, H., Yamasaki, M. O., Hendil, K. B., Toh-E, A., Tanahashi, N. & Tanaka, K., Jan 1 1996, In : European Journal of Biochemistry. 239, 3, p. 912-921 10 p.

Research output: Contribution to journalArticle

55 Scopus citations

cDNA cloning of p112, the largest regulatory subunit of the human 26S proteasome, and functional analysis of its yeast homologue, Sen3p

Yokota, K. Y., Kagawa, S., Shimizu, Y., Akioka, H., Tsurumi, C., Noda, C., Fujimuro, M., Yokosawa, H., Fujiwara, T., Takahashi, E. I., Ohba, M., Yamasaki, M. O., DeMartino, G. N., Slaughter, C. A., Toh-e, A. & Tanaka, K., Jun 1996, In : Molecular Biology of the Cell. 7, 6, p. 853-870 18 p.

Research output: Contribution to journalArticle

53 Scopus citations

CDNA cloning of p42, a shared subunit of two proteasome regulatory proteins, reveals a novel member of the AAA protein family

Fujiwara, T., Watanabe, T. K., Tanaka, K., Slaughter, C. A. & DeMartino, G. N., Jun 3 1996, In : FEBS Letters. 387, 2-3, p. 184-188 5 p.

Research output: Contribution to journalArticle

23 Scopus citations

Characterization of δ-sarcoglycan, a novel component of the oligomeric sarcoglycan complex involved in limb-girdle muscular dystrophy

Jung, D., Duclos, F., Apostol, B., Straub, V., Lee, J. C., Allamand, V., Venzke, D. P., Sunada, Y., Moomaw, C. R., Leveille, C. J., Slaughter, C. A., Crawford, T. O., McPherson, J. D. & Campbell, K. P., Dec 30 1996, In : Journal of Biological Chemistry. 271, 50, p. 32321-32329 9 p.

Research output: Contribution to journalArticle

79 Scopus citations

Functional studies of the ATP-binding subunits of PA700, an activator of 20S proteasome

Zagnitko, O. P., DeMartino, G. N. & Slaughter, C. A., Dec 1 1996, In : FASEB Journal. 10, 6

Research output: Contribution to journalArticle

Identification, purification, and characterization of a PA700-dependent activator of the proteasome

DeMartino, G. N., Proske, R. J., Moomaw, C. R., Strong, A. A., Song, X., Hisamatsu, H., Tanaka, K. & Slaughter, C. A., Feb 9 1996, In : Journal of Biological Chemistry. 271, 6, p. 3112-3118 7 p.

Research output: Contribution to journalArticle

124 Scopus citations

Molecular cloning of human phosphomevalonate kinase and identification of a consensus peroxisomal targeting sequence

Chambliss, K. L., Slaughter, C. A., Schreiner, R., Hoffmann, G. F. & Michael Gibson, K., Aug 5 1996, In : Journal of Biological Chemistry. 271, 29, p. 17330-17334 5 p.

Research output: Contribution to journalArticle

38 Scopus citations

Rat MHC-linked peptide transporter alleles strongly influence peptide binding by HLA-B27 but not B27-associated inflammatory disease

Simmons, W. A., Leong, L. Y. W., Satumtira, N., Butcher, G. W., Howard, J. C., Richardson, J. A., Slaughter, C. A., Hammer, R. E. & Taurog, J. D., Feb 15 1996, In : Journal of Immunology. 156, 4, p. 1661-1667 7 p.

Research output: Contribution to journalArticle

23 Scopus citations
1995

Azotobacter Vinelandii Citrate Synthase

Rault-Leonardon, M., Srere, P. A., Atkinson, M. A. L., Slaughter, C. A. & Moomaw, C. R., Jan 1 1995, In : Biochemistry. 34, 1, p. 257-263 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

cDNA cloning of a new putative ATPase subunit p45 of the human 26S proteasome, a homolog of yeast transcriptional factor Sug1p

Akiyama, K. Y., Yokota, K. Y., Kagawa, S., Shimbara, N., DeMartino, G. N., Slaughter, C. A., Noda, C. & Tanaka, K., Apr 17 1995, In : FEBS Letters. 363, 1-2, p. 151-156 6 p.

Research output: Contribution to journalArticle

59 Scopus citations

cDNA cloning of p40, a regulatory subunit of the human 26S proteasome, and a homolog of the Mov-34 gene product

Tsurumi, C., Demartino, G. N., Slaughter, C. A., Shimbara, N. & Tanaka, K., May 16 1995, In : Biochemical and Biophysical Research Communications. 210, 2, p. 600-608 9 p.

Research output: Contribution to journalArticle

29 Scopus citations

ERK phosphorylation potentiates Elk-1-mediated ternary complex formation and transactivation

Gille, H., Kortenjann, M., Thomae, O., Moomaw, C., Slaughter, C. A., Cobb, M. H. & Shaw, P. E., Jan 1 1995, In : EMBO Journal. 14, 5, p. 951-962 12 p.

Research output: Contribution to journalArticle

550 Scopus citations

Molecular cloning of the mature NAD+-dependent succinic semialdehyde dehydrogenase from rat and human: cDNA isolation, evolutionary homology, and tissue expression

Chambliss, K. L., Caudle, D. L., Hinson, D. D., Moomaw, C. R., Slaughter, C. A., Jakobs, C. & Gibson, K. M., Jan 6 1995, In : Journal of Biological Chemistry. 270, 1, p. 461-467 7 p.

Research output: Contribution to journalArticle

64 Scopus citations

Nin1p, a regulatory subunit of the 26S proteasome, is necessary for activation of Cdc28p kinase of Saccharomyces cerevisiae

Kominami -i., K., DeMartino, G. N., Moomaw, C. R., Slaughter, C. A., Shimbara, N., Fujimuro, M., Yokosawa, H., Hisamatsu, H., Tanahashi, N., Shimizu, Y., Tanaka, K. & Toh-e, A., Jan 1 1995, In : EMBO Journal. 14, 13, p. 3105-3115 11 p.

Research output: Contribution to journalArticle

92 Scopus citations

Nonclassical binding of formylated peptide in crystal structure of the MHC class lb molecule H2-M3

Wang, C. R., Castaño, A. R., Peterson, P. A., Slaughter, C., Fischer Lindahl, K. & Deisenhofer, J., Aug 25 1995, In : Cell. 82, 4, p. 655-664 10 p.

Research output: Contribution to journalArticle

131 Scopus citations

Photoaffinity labeling of a peptide substrate to myosin light chain kinase

Gao, Z. H., Zhi, G., Herring, B. P., Moomaw, C., Deogny, L., Slaughter, C. A. & Stull, J. T., Jan 1 1995, In : Journal of Biological Chemistry. 270, 17, p. 10125-10135 11 p.

Research output: Contribution to journalArticle

19 Scopus citations

Primary structures of two homologous subunits of PA28, a γ-interferon-inducible protein activator of the 20S proteasome

Joon Young Ahn, Y. A., Nobuyuki Tanahashi, T., Kin-ya Akiyama, A., Hiroshi Hisamatsu, H., Chiseko Noda, N., Keiji Tanaka, T., Chin Ha Chung, H. C., Naoki Shibmara, S., Willy, P. J., Mott, J. D., Slaughter, C. A. & DeMartino, G. N., Jun 5 1995, In : FEBS Letters. 366, 1, p. 37-42 6 p.

Research output: Contribution to journalArticle

168 Scopus citations

Purification of an interleukin-1β converting enzyme-related cysteine protease that cleaves sterol regulatory element-binding proteins between the leucine zipper and transmembrane domains

Wang, X., Pai, J. T., Wiedenfeld, E. A., Medina, J. C., Slaughter, C. A., Goldstein, J. L. & Brown, M. S., Jan 1 1995, In : Journal of Biological Chemistry. 270, 30, p. 18044-18050 7 p.

Research output: Contribution to journalArticle

129 Scopus citations

v-rel Induces ectopic expression of an adhesion molecule, DM-GRASP, during B-lymphoma development

Zhang, G., Slaughter, C. A. & Humphries, E. H., Jan 1 1995, In : Molecular and Cellular Biology. 15, 3, p. 1806-1816 11 p.

Research output: Contribution to journalArticle

26 Scopus citations

β–sarcoglycan: Characterization and role in limb–girdle muscular dystrophy linked to 4q12

Lim, L. E., Duclos, F., Broux, O., Nathalie, B., Sunada, Y., Allamand, V., Meyer, J., Richard, I., Moomaw, C., Slaughter, C. A., Tomé, F. M. S., Fardeau, M., Jackson, C. E., Beckmann, J. S. & Campbell, K. P., Nov 1995, In : Nature Genetics. 11, 3, p. 257-265 9 p.

Research output: Contribution to journalArticle

410 Scopus citations
1994

Conserved domain structure of β-neurexins. Unusual cleaved signal sequences in receptor-like neuronal cell-surface proteins

Ushkaryov, Y. A., Hata, Y., Ichtchenko, K., Moomaw, C., Afendis, S., Slaughter, C. A. & Sudhof, T. C., Jan 1 1994, In : Journal of Biological Chemistry. 269, 16, p. 11987-11992 6 p.

Research output: Contribution to journalArticle

116 Scopus citations

ECE-1: A membrane-bound metalloprotease that catalyzes the proteolytic activation of big endothelin-1

Xu, D., Emoto, N., Giaid, A., Slaughter, C., Kaw, S., deWit, D. & Yanagisawa, M., Aug 12 1994, In : Cell. 78, 3, p. 473-485 13 p.

Research output: Contribution to journalArticle

833 Scopus citations

Heterogeneity of the 59-kDa dystrophin-associated protein revealed by cDNA cloning and expression

Yang, B., Ibraghimov-Beskrovnaya, O., Moomaw, C. R., Slaughter, C. A. & Campbell, K. P., Feb 25 1994, In : Journal of Biological Chemistry. 269, 8, p. 6040-6044 5 p.

Research output: Contribution to journalArticle

96 Scopus citations

Identification, purification, and characterization of a high molecular weight, ATP-dependent activator (PA700) of the 20 S proteasome

Chu-Ping, M., Vu, J. H., Proske, R. J., Slaughter, C. A. & DeMartino, G. N., Feb 4 1994, In : Journal of Biological Chemistry. 269, 5, p. 3539-3547 9 p.

Research output: Contribution to journalArticle

212 Scopus citations

Molecular cloning and expression of palmitoyl-protein thioesterase

Camp, L. A., Verkruyse, L. A., Afendis, S. J., Slaughter, C. A. & Hofmann, S. L., Sep 16 1994, In : Journal of Biological Chemistry. 269, 37, p. 23212-23219 8 p.

Research output: Contribution to journalArticle

180 Scopus citations

PA28, an activator of the 20 S proteasome, is composed of two nonidentical but homologous subunits

Mott, J. D., Pramanik, B. C., Moomaw, C. R., Afendis, S. J., DeMartino, G. N. & Slaughter, C. A., Dec 16 1994, In : Journal of Biological Chemistry. 269, 50, p. 31466-31471 6 p.

Research output: Contribution to journalArticle

55 Scopus citations

PA700, an ATP-dependent activator of the 20 S proteasome, is an ATPase containing multiple members of a nucleotide-binding protein family

DeMartino, G. N., Moomaw, C. R., Zagnitko, O. P., Proske, R. J., Chu-Ping, M., Afendis, S. J., Swaffield, J. C. & Slaughter, C. A., Aug 19 1994, In : Journal of Biological Chemistry. 269, 33, p. 20878-20884 7 p.

Research output: Contribution to journalArticle

190 Scopus citations

Positional effects in the neprilysin (neutral endopeptidase) reaction

Quay, T., Slaughter, C. A., Davis, T. P., Merrill, B. J. & Hersh, L. B., Jan 1 1994, In : Archives of Biochemistry and Biophysics. 308, 1, p. 133-136 4 p.

Research output: Contribution to journalArticle

9 Scopus citations

Proteolytic processing of ovalbumin and β-galactosidase by the proteasome to yield antigenic peptides

Dick, L. R., Aldrich, C., Jameson, S. C., Moomaw, C. R., Pramanik, B. C., Doyle, C. K., DeMartino, G. N., Bevan, M. J., Forman, J. M. & Slaughter, C. A., Apr 15 1994, In : Journal of Immunology. 152, 8, p. 3884-3894 11 p.

Research output: Contribution to journalArticle

168 Scopus citations

Rhodobacter capsulatus Contains a Novel cb-Type Cytochrome c Oxidase without a CuA Center

Gray, K. A., Grooms, M., Myllykallio, H., Daldal, F., Moomaw, C. & Slaughter, C. A., Mar 1 1994, In : Biochemistry. 33, 10, p. 3120-3127 8 p.

Research output: Contribution to journalArticle

138 Scopus citations

Solid-phase synthesis of biologically active lipopeptides as analogs for spirochetal lipoproteins

DeOgny, L., Pramanik, B. C., Arndt, L. L., Jones, J. D., Rush, J., Slaughter, C. A., Radolf, J. D. & Norgard, M. V., Mar 1 1994, In : Peptide research. 7, 2, p. 91-97 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

The 100 kDa haem:haemopexin‐binding protein of Haemophilus Influenzae: structure and localization

Cope, L. D., Thomas, S. E., Latimer, J. L., Slaughter, C. A., Müller‐Eberhard, U. & Hansen, E. J., Jan 1 1994, In : Molecular Microbiology. 13, 5, p. 863-873 11 p.

Research output: Contribution to journalArticle

58 Scopus citations
1993

ADP-ribosylation factor, a small GTP-dependent regulatory protein, stimulates phospholipase D activity

Brown, H. A., Gutowski, S., Moomaw, C. R., Slaughter, C. A. & Sternwels, P. C., Dec 17 1993, In : Cell. 75, 6, p. 1137-1144 8 p.

Research output: Contribution to journalArticle

788 Scopus citations