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  • 19 Similar Profiles
Indoleamine-Pyrrole 2,3,-Dioxygenase Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences
Dendritic Cells Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Regulatory T-Lymphocytes Medicine & Life Sciences
T-cells Chemical Compounds
Tryptophan Medicine & Life Sciences
Graft vs Host Disease Medicine & Life Sciences

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Projects 1995 2019

Indoleamine-Pyrrole 2,3,-Dioxygenase
Dendritic Cells
Indoleamine-Pyrrole 2,3,-Dioxygenase
Dendritic Cells
Neoplasm Antigens
Indoleamine-Pyrrole 2,3,-Dioxygenase
Neoplasm Antigens
Drug Therapy
CD40 Ligand
Indoleamine-Pyrrole 2,3,-Dioxygenase
Macrophage Colony-Stimulating Factor

Research Output 1987 2019

Dendritic Cell Expression of Retinal Aldehyde Dehydrogenase-2 Controls Graft-versus-Host Disease Lethality

Thangavelu, G., Lee, Y. C., Loschi, M., Schaechter, K. M., Feser, C. J., Koehn, B. H., Nowak, E. C., Zeiser, R., Serody, J. S., Murphy, W. J., Munn, D. H., Chambon, P., Noelle, R. J. & Blazar, B. R., May 1 2019, In : Journal of immunology (Baltimore, Md. : 1950). 202, 9, p. 2795-2805 11 p.

Research output: Contribution to journalArticle

Retinal Dehydrogenase
Aldehyde Dehydrogenase
Graft vs Host Disease
Dendritic Cells

ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression

Cao, Y., Trillo-Tinoco, J., Sierra, R. A., Anadon, C., Dai, W., Mohamed, E., Cen, L., Costich, T. L., Magliocco, A., Marchion, D., Klar, R., Michel, S., Jaschinski, F., Reich, R. R., Mehrotra, S., Cubillos-Ruiz, J. R., Munn, D. H., Conejo-Garcia, J. R. & Rodriguez, P. C., Dec 1 2019, In : Nature Communications. 10, 1, 1280.

Research output: Contribution to journalArticle

Open Access
Transcription Factor CHOP
endoplasmic reticulum
Endoplasmic Reticulum Stress
11 Citations (Scopus)

Activation of p53 in Immature Myeloid Precursor Cells Controls Differentiation into Ly6c+CD103+ Monocytic Antigen-Presenting Cells in Tumors

Sharma, M. D., Rodriguez, P. C., Koehn, B. H., Baban, B., Cui, Y., Guo, G., Shimoda, M., Pacholczyk, R. W., Shi, H., Lee, E. J., Xu, H., Johnson, T. S., He, Y., Mergoub, T., Venable, C., Bronte, V., Wolchok, J. D., Blazar, B. R. & Munn, D. H., Jan 16 2018, In : Immunity. 48, 1, p. 91-106.e6

Research output: Contribution to journalArticle

Antigen-Presenting Cells
Myeloid Cells
Cell Differentiation

Alteration of Tumor Metabolism by CD4+ T Cells Leads to TNF-α-Dependent Intensification of Oxidative Stress and Tumor Cell Death

Habtetsion, T., Ding, Z-C., Pi, W., Li, T., Lu, C., Chen, T., Xi, C., Spartz, H., Liu, K., Hao, Z., Mivechi, N. F., Huo, Y., Blazar, B. R., Munn, D. H. & Zhou, G., Aug 7 2018, In : Cell Metabolism. 28, 2, p. 228-242.e6

Research output: Contribution to journalArticle

Oxidative Stress
Cell Death
Adoptive Immunotherapy
14 Citations (Scopus)

Apoptotic cell-induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans article

Shinde, R., Hezaveh, K., Halaby, M. J., Kloetgen, A., Chakravarthy, A., Da Silva Medina, T., Deol, R., Manion, K. P., Baglaenko, Y., Eldh, M., Lamorte, S., Wallace, D., Chodisetti, S. B., Ravishankar, B., Liu, H., Chaudhary, K., Munn, D. H., Tsirigos, A., Madaio, M. P., Gabrielsson, S. & 4 othersTouma, Z., Wither, J., De Carvalho, D. D. & McGaha, T. L., Jun 1 2018, In : Nature Immunology. 19, 6, p. 571-582 12 p.

Research output: Contribution to journalArticle

Systemic Lupus Erythematosus
Peripheral Tolerance
Pattern Recognition Receptors