Sharad A Ghamande

Department Chair

  • 896 Citations
  • 17 h-Index
19952020

Research output per year

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Research Output

  • 896 Citations
  • 17 h-Index
  • 38 Article
  • 2 Letter
2020

A 73-gene proliferative transcriptomic signature predicts uterine serous carcinoma patient survival and response to primary therapy

Tran, L. K. H., Tran, P. M. H., Mysona, D. P., Purohit, S. B., Myers, E., Lee, W. S., Dun, B., Xu, D., Liu, H., Hopkins, D., Nechtman, J., Scelsi, C. L., Mittal, P. K., Kleven, D., Wallbillich, J. J., Rungruang, B., Ghamande, S. & She, J. X., Jan 1 2020, (Accepted/In press) In : Gynecologic Oncology.

Research output: Contribution to journalArticle

A Randomized Phase II Trial of Epigenetic Priming with Guadecitabine and Carboplatin in Platinum-resistant, Recurrent Ovarian Cancer

Oza, A. M., Matulonis, U. A., Secord, A. A., Nemunaitis, J., Roman, L. D., Blagden, S. P., Banerjee, S., McGuire, W. P., Ghamande, S., Birrer, M. J., Fleming, G. F., Markham, M. J., Hirte, H. W., Provencher, D. M., Basu, B., Kristeleit, R., Armstrong, D. K., Schwartz, B., Braly, P., Hall, G. D. & 8 others, Nephew, K. P., Jueliger, S., Oganesian, A., Naim, S., Hao, Y., Keer, H., Azab, M. & Matei, D., Mar 1 2020, In : Clinical Cancer Research. 26, 5, p. 1009-1016 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Clinical calculator predictive of chemotherapy benefit in stage 1A uterine papillary serous cancers

Mysona, D. P., Tran, L. K. H., Tran, P. M. H., Gehrig, P. A., Van Le, L., Ghamande, S., Rungruang, B. J., Java, J., Mann, A. K., Liao, J., Kapp, D. S., Santos, B. D., She, J. X. & Chan, J. K., Jan 2020, In : Gynecologic Oncology. 156, 1, p. 77-84 8 p.

Research output: Contribution to journalArticle

Sequential Ipilimumab after Chemoradiotherapy in Curative-Intent Treatment of Patients with Node-Positive Cervical Cancer

Mayadev, J. S., Enserro, D., Lin, Y. G., Da Silva, D. M., Lankes, H. A., Aghajanian, C., Ghamande, S., Moore, K. N., Kennedy, V. A., Fracasso, P. M. & Schilder, R. J., Jan 2020, In : JAMA Oncology. 6, 1, p. 92-99 8 p.

Research output: Contribution to journalArticle

2019

A combined score of clinical factors and serum proteins can predict time to recurrence in high grade serous ovarian cancer

Mysona, D., Pyrzak, A., Purohit, S., Zhi, W., Sharma, A., Tran, L., Tran, P., Bai, S., Rungruang, B., Ghamande, S. & She, J. X., Mar 2019, In : Gynecologic Oncology. 152, 3, p. 574-580 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Alisertib in Combination with Weekly Paclitaxel in Patients with Advanced Breast Cancer or Recurrent Ovarian Cancer: A Randomized Clinical Trial

Falchook, G., Coleman, R. L., Roszak, A., Behbakht, K., Matulonis, U., Ray-Coquard, I., Sawrycki, P., Duska, L. R., Tew, W., Ghamande, S. A., Lesoin, A., Schwartz, P. E., Buscema, J., Fabbro, M., Lortholary, A., Goff, B., Kurzrock, R., Martin, L. P., Gray, H. J., Fu, S. & 6 others, Sheldon-Waniga, E., Lin, H. M., Venkatakrishnan, K., Zhou, X., Leonard, E. J. & Schilder, R. J., Jan 2019, In : JAMA Oncology. 5, 1

Research output: Contribution to journalArticle

12 Scopus citations

Bovine Pericardial Graft for Second-Trimester Cesarean Scar Dehiscence

Stephens, A., Patel, K., Davis, J. & Ghamande, S., Feb 1 2019, In : Obstetrics and gynecology. 133, 2, p. 364-367 4 p.

Research output: Contribution to journalArticle

Trebananib or placebo plus carboplatin and paclitaxel as first-line treatment for advanced ovarian cancer (TRINOVA-3/ENGOT-ov2/GOG-3001): a randomised, double-blind, phase 3 trial

TRINOVA-3/ENGOT-ov2/GOG-3001 investigators, Jun 2019, In : The Lancet Oncology. 20, 6, p. 862-876 15 p.

Research output: Contribution to journalArticle

5 Scopus citations
2018

A phase i clinical trial of guadecitabine and carboplatin in platinum-resistant, recurrent ovarian cancer: Clinical, pharmacokinetic, and pharmacodynamic analyses

Matei, D., Ghamande, S., Roman, L., Secord, A. A., Nemunaitis, J., Markham, M. J., Nephew, K. P., Jueliger, S., Oganesian, A., Naim, S., Su, X. Y., Keer, H., Azab, M. & Fleming, G. F., May 15 2018, In : Clinical Cancer Research. 24, 10, p. 2285-2293 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

Evaluation of a Streamlined Oncologist-Led BRCA Mutation Testing and Counseling Model for Patients With Ovarian Cancer

Colombo, N., Huang, G., Scambia, G., Chalas, E., Pignata, S., Fiorica, J., Vanle, L., Ghamande, S. A., González-Santiago, S., Bover, I., Suárez, B. G., Green, A., Huot-Marchand, P., Bourhis, Y., Karve, S. & Blakeley, C., May 1 2018, In : Journal of Clinical Oncology. 36, 13, p. 1300-1307 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

Multiplex glycan bead array for high throughput and high content analyses of glycan binding proteins

Purohit, S. B., Li, T., Guan, W., Song, X., Song, J., Tian, Y., Li, L., Sharma, A. K., Dun, B., Mysona, D., Ghamande, S. A., Rungruang, B. J., Cummings, R. D., Wang, P. G. & She, J-X., Dec 1 2018, In : Nature communications. 9, 1, 258.

Research output: Contribution to journalArticle

20 Scopus citations

Proteomic approach to identify biomarkers for invasive cervix cancer - a prospective pilot study

Mysona, D., Pyrzak, A., Allen, J., Powell, M., Kleven, D., Zhi, W., Sharma, A., Bai, S., She, J. X., Rungruang, B. & Ghamande, S., Jan 1 2018, In : European Journal of Gynaecological Oncology. 39, 5, p. 737-742 6 p.

Research output: Contribution to journalArticle

Targeting EGFR/HER2/HER3 with a Three-in-One Aptamer-siRNA Chimera Confers Superior Activity against HER2+ Breast Cancer

Yu, X., Ghamande, S. A., Liu, H., Xue, L., Zhao, S., Tan, W., Zhao, L., Tang, S-C., Wu, D., Korkaya, H., Maihle, N. J. & Liu, H., Mar 2 2018, In : Molecular Therapy - Nucleic Acids. 10, p. 317-330 14 p.

Research output: Contribution to journalArticle

19 Scopus citations
2017

Healthy lifestyle intervention for African American uterine cancer survivors: Study protocol

Stewart, J. L., Besenyi, G. B., Williams, L. B., Burt, V., Anglin, J. C., Ghamande, S. A. & Coughlin, S. S., Dec 2017, In : Contemporary Clinical Trials Communications. 8, p. 11-17 7 p.

Research output: Contribution to journalArticle

1 Scopus citations
2016

Atypical presentations of molar pregnancy: Diagnostic roles of imaging, ß-human chorionic gonadotropin measurement, and p57 immunostaining

Mohamed, S. A., Al-Hendy, A., Ghamande, S., Chaffin, J. & Browne, P., Mar 1 2016, In : Journal of Ultrasound in Medicine. 35, 3, p. 643-649 7 p.

Research output: Contribution to journalArticle

2015

Phase II study of the PI3K inhibitor pilaralisib (SAR245408; XL147) in patients with advanced or recurrent endometrial carcinoma

Matulonis, U., Vergote, I., Backes, F., Martin, L. P., McMeekin, S., Birrer, M., Campana, F., Xu, Y., Egile, C. & Ghamande, S. A., Feb 1 2015, In : Gynecologic Oncology. 136, 2, p. 246-253 8 p.

Research output: Contribution to journalArticle

52 Scopus citations
2014

A phase 1 open-label, sequential dose-escalation study investigating the safety, tolerability, and pharmacokinetics of intravenous TLC388 administered to patients with advanced solid tumors

Ghamande, S., Lin, C. C., Cho, D. C., Shapiro, G. I., Kwak, E. L., Silverman, M. H., Tseng, Y., Kuo, M. W., Mach, W. B., Hsu, S. C., Coleman, T., Yang, J. C. H., Cheng, A. L., Ghalib, M. H., Chuadhary, I. & Goel, S., Jun 2014, In : Investigational New Drugs. 32, 3, p. 445-451 7 p.

Research output: Contribution to journalArticle

12 Scopus citations
12 Scopus citations

Weekly AUC2 carboplatin in acquired platinum-resistant ovarian cancer with or without oral phenoxodiol, a sensitizer of platinum cytotoxicity: The phase III OVATURE multicenter randomized study

Fotopoulou, C., Vergote, I., Mainwaring, P., Bidzinski, M., Vermorken, J. B., Ghamande, S. A., Harnett, P., del Prete, S. A., Green, J. A., Spaczynski, M., Blagden, S., Gore, M., Ledermann, J., Kaye, S. & Gabra, H., 2014, In : Annals of Oncology. 25, 1, p. 160-165 6 p., mdt515.

Research output: Contribution to journalArticle

23 Scopus citations
2013

PRECEDENT: A randomized phase II trial comparing vintafolide (EC145) and pegylated liposomal doxorubicin (PLD) in combination versus PLD alone in patients with platinum-resistant ovarian cancer

Naumann, R. W., Coleman, R. L., Burger, R. A., Sausville, E. A., Kutarska, E., Ghamande, S. A., Gabrail, N. Y., DePasquale, S. E., Nowara, E., Gilbert, L., Gersh, R. H., Teneriello, M. G., Harb, W. A., Konstantinopoulos, P. A., Penson, R. T., Symanowski, J. T., Lovejoy, C. D., Leamon, C. P., Morgenstern, D. E. & Messmann, R. A., Dec 10 2013, In : Journal of Clinical Oncology. 31, 35, p. 4400-4406 7 p.

Research output: Contribution to journalArticle

122 Scopus citations

Serum protein profile at remission can accurately assess therapeutic outcomes and survival for serous ovarian cancer

Wang, J., Sharma, A., Ghamande, S. A., Bush, S., Ferris, D., Zhi, W., He, M., Wang, M., Wang, X., Miller, E., Hopkins, D., Macfee, M., Guan, R., Tang, J. & She, J. X., Nov 11 2013, In : PloS one. 8, 11, e78393.

Research output: Contribution to journalArticle

9 Scopus citations
2012

Phase II study of MLN8237 (alisertib), an investigational Aurora A kinase inhibitor, in patients with platinum-resistant or -refractory epithelial ovarian, fallopian tube, or primary peritoneal carcinoma

Matulonis, U. A., Sharma, S., Ghamande, S. A., Gordon, M. S., Del Prete, S. A., Ray-Coquard, I., Kutarska, E., Liu, H., Fingert, H., Zhou, X., Danaee, H. & Schilder, R. J., Oct 1 2012, In : Gynecologic Oncology. 127, 1, p. 63-69 7 p.

Research output: Contribution to journalArticle

100 Scopus citations
2008

A phase 2, randomized, double-blind, placebo-controlled trial of clinical activity and safety of subcutaneous Å6 in women with asymptomatic CA125 progression after first-line chemotherapy of epithelial ovarian cancer

Ghamande, S. A., Silverman, M. H., Huh, W., Behbakht, K., Ball, G., Cuasay, L., Würtz, S. O., Brunner, N. & Gold, M. A., Oct 1 2008, In : Gynecologic Oncology. 111, 1, p. 89-94 6 p.

Research output: Contribution to journalArticle

34 Scopus citations
2006

Up-regulation of the amino acid transporter ATB0,+ (SLC6A14) in carcinoma of the cervix

Gupta, N., Prasad, P. D., Ghamande, S., Moore-Martin, P., Herdman, A. V., Martindale, R. G., Podolsky, R., Mager, S., Ganapathy, M. E. & Ganapathy, V., Jan 1 2006, In : Gynecologic Oncology. 100, 1, p. 8-13 6 p.

Research output: Contribution to journalArticle

51 Scopus citations
2004

Efficacy of adjuvant CYVADIC chemotherapy in early-stage uterine sarcomas: Results of long-term follow-up

Odunsi, K., Moneke, V., Tammela, J., Ghamande, S. A., Seago, P., Driscoll, D., Marchetti, D., Baker, T. & Lele, S., Jul 1 2004, In : International Journal of Gynecological Cancer. 14, 4, p. 659-664 6 p.

Research output: Contribution to journalArticle

26 Scopus citations
2003

Weekly paclitaxel in patients with recurrent or persistent advanced ovarian cancer

Ghamande, S., Lele, S., Marchetti, D., Baker, T. & Odunsi, K., Mar 1 2003, In : International Journal of Gynecological Cancer. 13, 2, p. 142-147 6 p.

Research output: Contribution to journalArticle

32 Scopus citations
2002

Evaluation of prognostic factors and treatment modalities in ovarian cancer patients with brain metastases

Anupol, N., Ghamande, S., Odunsi, K., Driscoll, D. & Lele, S., Jan 1 2002, In : Gynecologic Oncology. 85, 3, p. 487-492 6 p.

Research output: Contribution to journalArticle

62 Scopus citations

Evaluation of β1,4-galactosyltransferase as a potential biomarker for the detection of subclinical disease after the completion of primary therapy for ovarian cancer

Odunsi, K., Ghamande, S., Chandrasekaran, E. V., Ta, A., Moysich, K. B., Driscoll, D., Matta, K. & Lele, S., Sep 2002, In : American journal of obstetrics and gynecology. 187, 3, p. 575-580 6 p.

Research output: Contribution to journalArticle

11 Scopus citations
2001

Human ovarian cancer, lymphoma spleen, and bovine milk GlcNAc:β1,4Gal/GalNAc transferases: Two molecular species in ovarian tumor and induction of GalNAcβ1,4Glc synthesis by α-lactalbumin

Chandrasekaran, E. V., Chawda, R., Piskorz, C., Locke, R. D., Ta, A., Sharad, G., Odunsi, K., Lele, S. & Matta, K. L., Aug 23 2001, In : Carbohydrate Research. 334, 2, p. 105-118 14 p.

Research output: Contribution to journalArticle

7 Scopus citations

Recombinant CD40 ligand therapy has significant antitumor effects on CD40-positive ovarian tumor xenografts grown in SCID mice and demonstrates an augmented effect with cisplatin

Ghamande, S., Lele, S., Hylander, B. L., Oflazoglu, E., Repasky, E. A. & Fanslow, W., Oct 15 2001, In : Cancer Research. 61, 20, p. 7556-7562 7 p.

Research output: Contribution to journalArticle

83 Scopus citations

The impact of pre-therapy extraperitoneal surgical staging on the evaluation and treatment of patients with locally advanced cervical cancer

Odunsi, K. O., Lele, S., Ghamande, S., Seago, P. & Driscoll, D. L., Dec 29 2001, In : European Journal of Gynaecological Oncology. 22, 5, p. 325-330 6 p.

Research output: Contribution to journalArticle

40 Scopus citations
1999

Effective management of pelvic lymphocysts by laparoscopic marsupialization.

Recio, F. O., Ghamande, S. A., Hempling, R. E. & Piver, M. S., Jan 1 1999, In : JSLS : Journal of the Society of Laparoendoscopic Surgeons / Society of Laparoendoscopic Surgeons. 3, 2, p. 97-102 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

First-line chemotherapy with paclitaxel and platinum for advanced and recurrent cancer of the cervix - A phase II study

Piver, M. S., Ghamande, S. A., Eltabbakh, G. H. & O'Neill-Coppola, C., Dec 1999, In : Gynecologic Oncology. 75, 3, p. 334-337 4 p.

Research output: Contribution to journalArticle

50 Scopus citations
13 Scopus citations
1997

Adenocarcinoma of the ileum with an enterotubal fistula presenting as an adnexal mass

Hamid, A. M., Ghamande, S. A. & Kasznicadagger, J., Feb 1997, In : Gynecologic Oncology. 64, 2, p. 270-273 4 p.

Research output: Contribution to journalArticle

5 Scopus citations

A randomized trial of misoprostol and oxytocin for induction of labor: Safety and efficacy [3] (multiple letter)

Feingold, M., Ghamande, S., Kramer, R. L., Gilson, G. J. & Quails, C. R., Jan 1 1997, In : Obstetrics and gynecology. 90, 1, p. 155-156 2 p.

Research output: Contribution to journalLetter

1996

High levels of CA-125 in a case of a parasitic leiomyoma presenting as an abdominal mass

Ghamande, S. A., Eleonu, B. & Hamid, A. M., May 1996, In : Gynecologic Oncology. 61, 2, p. 297-298 2 p.

Research output: Contribution to journalArticle

16 Scopus citations
1995

Mucinous adenocarcinomas of the vulva

Ghamande, S. A., Kasznica, J., Griffiths, C. T., Finkler, N. J. & Hamid, A. M., Apr 1995, In : Gynecologic Oncology. 57, 1, p. 117-120 4 p.

Research output: Contribution to journalArticle

32 Scopus citations