• 246 Citations
  • 8 h-Index
20022019

Research output per year

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Research Output

  • 246 Citations
  • 8 h-Index
  • 17 Article
  • 2 Letter
  • 1 Review article
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Article
2019

Conjugate prodrug AN-233 induces fetal hemoglobin expression in sickle erythroid progenitors and β-YAC transgenic mice

Oseghale, A. R., Zhu, X., Li, B., Peterson, K. R., Nudelman, A., Rephaeli, A., Xu, H. & Pace, B. S., Nov 2019, In : Blood Cells, Molecules, and Diseases. 79, 102345.

Research output: Contribution to journalArticle

1 Scopus citations

Feature article: δ-Aminolevulinate induces fetal hemoglobin expression by enhancing cellular heme biosynthesis

Liu, L., Zhu, X., Yu, A., Ward, C. M. & Pace, B. S., Oct 1 2019, In : Experimental Biology and Medicine. 244, 14, p. 1220-1232 13 p.

Research output: Contribution to journalArticle

Open Access

MIR-144-mediated NRF2 gene silencing inhibits fetal hemoglobin expression in sickle cell disease

Li, B., Zhu, X., Ward, C. M., Starlard-Davenport, A., Takezaki, M., Berry, A., Ward, A., Wilder, C., Neunert, C., Kutlar, A. & Pace, B. S., Feb 2019, In : Experimental Hematology. 70, p. 85-96.e5

Research output: Contribution to journalArticle

8 Scopus citations
2018

Loss of NRF2 function exacerbates the pathophysiology of sickle cell disease in a transgenic mouse model

Zhu, X., Xi, C., Thomas, B. & Pace, B. S., Feb 1 2018, In : Blood. 131, 5, p. 558-562 5 p.

Research output: Contribution to journalArticle

9 Scopus citations
2017

Hydroxyurea differentially modulates activator and repressors of γ-globin gene in erythroblasts of responsive and non-responsive patients with sickle cell disease in correlation with index of hydroxyurea responsiveness

Zhu, X., Hu, T., Ho, M. H., Wang, Y., Yu, M., Patel, N., Pi, W., Choi, J-H., Xu, H., Ganapathy, V., Kutlar, F., Kutlar, A. & Tuan Lo, D., Nov 30 2017, In : Haematologica. 102, 12, p. 1995-2004 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Hypermethylated LTR retrotransposon exhibits enhancer activity

Hu, T., Zhu, X., Pi, W., Yu, M., Shi, H. & Tuan Lo, D., Mar 4 2017, In : Epigenetics. 12, 3, p. 226-237 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

Long non-coding RNAs transcribed by ERV-9 LTR retrotransposon act in cis to modulate long-range LTR enhancer function

Hu, T., Pi, W., Zhu, X., Yu, M., Ha, H., Shi, H., Choi, J-H. & Tuan Lo, D., Jan 1 2017, In : Nucleic Acids Research. 45, 8, p. 4479-4492 14 p.

Research output: Contribution to journalArticle

9 Scopus citations
2012

NF-Y Recruits Both Transcription Activator and Repressor to Modulate Tissue- and Developmental Stage-Specific Expression of Human γ-Globin Gene

Zhu, X., Wang, Y., Pi, W., Liu, H., Wickrema, A. & Tuan Lo, D., Oct 10 2012, In : PloS one. 7, 10, e47175.

Research output: Contribution to journalArticle

22 Scopus citations
2010

Long-range function of an intergenic retrotransposon

Pi, W., Zhu, X., Wu, M., Wang, Y., Fulzele, S. T., Eroglu, A., Ling, J. & Tuan Lo, D., Jul 20 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 29, p. 12992-12997 6 p.

Research output: Contribution to journalArticle

48 Scopus citations
2008

Evaluation of Glu11 and Gly8 of the H5N1 influenza hemagglutinin fusion peptide in membrane fusion using pseudotype virus and reverse genetics

Su, Y., Zhu, X., Wang, Y., Wu, M. & Tien, P., Feb 1 2008, In : Archives of Virology. 153, 2, p. 247-257 11 p.

Research output: Contribution to journalArticle

5 Scopus citations
2007

A facilitated tracking and transcription mechanism of long-range enhancer function

Zhu, X., Ling, J., Zhang, L., Pi, W., Wu, M. & Tuan Lo, D., Aug 1 2007, In : Nucleic Acids Research. 35, 16, p. 5532-5544 13 p.

Research output: Contribution to journalArticle

60 Scopus citations
2005

The long terminal repeat (LTR) of ERV-9 human endogenous retrovirus binds to NF-Y in the assembly of an active LTR enhancer complex NF-Y/MZF1/GATA-2

Yu, X., Zhu, X., Pi, W., Ling, J., Ko, L., Takeda, Y. & Tuan, D., Oct 21 2005, In : Journal of Biological Chemistry. 280, 42, p. 35184-35194 11 p.

Research output: Contribution to journalArticle

35 Scopus citations
2004

Binding of trans-acting protein AngCP to the CCAAT-containing motifs in Aspergillus niger glaA promoter

Zhu, X., Qiu, R., Liu, L. & Tang, G., Apr 2004, In : Progress in Natural Science. 14, 4, p. 338-343 6 p.

Research output: Contribution to journalArticle

The synergetic effects of two CCAAT boxes in Aspergillus niger glaA gene promoter on activation of PglaA transcription

Zhu, X., Wang, H. M., Qiu, R., Liu, L., Dong, Z. & Tang, G., Dec 1 2004, In : Science in China, Series C: Life Sciences. 47, 2, p. 139-147 9 p.

Research output: Contribution to journalArticle

3 Scopus citations
2003

Improving heterologous gene expression in Aspergillus niger by introducing multiple copies of protein-binding sequence containing CCAAT to the promoter

Liu, L., Liu, J., Qiu, R. X., Zhu, X., Dong, Z. Y. & Tang, G. M., Jun 12 2003, In : Letters in Applied Microbiology. 36, 6, p. 358-361 4 p.

Research output: Contribution to journalArticle

20 Scopus citations
2002

Construction of recipient strain of expression-secretion system in filamentous fungi

Liu, L., Liu, J., Qiu, R. X., Zhu, X. & Tang, G. M., Nov 2002, In : Sheng wu gong cheng xue bao = Chinese journal of biotechnology. 18, 6, p. 667-670 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

Detection of a protein, AngCP, which binds specifically to the three upstream regions of glaA gene in A. niger T21

Qiu, R., Zhu, X., Liu, L. & Tang, G., Dec 1 2002, In : Science in China, Series C: Life Sciences. 45, 5, p. 527-537 11 p.

Research output: Contribution to journalArticle

4 Scopus citations