Abstract
Four homozygotes for β-thalassemia with normal hemoglobins A2 and F were studied. The absence or scarcity of transfusion requirement and comparatively low hemoglobin F content were the most important findings. Both parents of 3 patients showed the findings of β-thalassemia with normal hemoglobins A2 and F. Biosynthetic studies in 2 patients and both their parents showed moderate or mild β-chain deficiency. The possible reason for this comparatively mild course of a β-thalassemia syndrome lies in a mild deficit in β-chain production.
Original language | English (US) |
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Pages (from-to) | 57-61 |
Number of pages | 5 |
Journal | Acta Haematologica |
Volume | 67 |
Issue number | 1 |
DOIs | |
State | Published - Jan 1 1982 |
Externally published | Yes |
ASJC Scopus subject areas
- Hematology