β-Thalassemia intermedia homozygous for normal hemoglobin A2 β-thalassemia. Study in four families

M. Aksoy, E. Bermek, G. Almis, A. Kutlar

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Four homozygotes for β-thalassemia with normal hemoglobins A2 and F were studied. The absence or scarcity of transfusion requirement and comparatively low hemoglobin F content were the most important findings. Both parents of 3 patients showed the findings of β-thalassemia with normal hemoglobins A2 and F. Biosynthetic studies in 2 patients and both their parents showed moderate or mild β-chain deficiency. The possible reason for this comparatively mild course of a β-thalassemia syndrome lies in a mild deficit in β-chain production.

Original languageEnglish (US)
Pages (from-to)57-61
Number of pages5
JournalActa Haematologica
Volume67
Issue number1
DOIs
Publication statusPublished - Jan 1 1982
Externally publishedYes

    Fingerprint

ASJC Scopus subject areas

  • Hematology

Cite this