β-Thalassemia intermedia homozygous for normal hemoglobin A2 β-thalassemia. Study in four families

M. Aksoy, E. Bermek, G. Almis, Abdullah Kutlar

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Four homozygotes for β-thalassemia with normal hemoglobins A2 and F were studied. The absence or scarcity of transfusion requirement and comparatively low hemoglobin F content were the most important findings. Both parents of 3 patients showed the findings of β-thalassemia with normal hemoglobins A2 and F. Biosynthetic studies in 2 patients and both their parents showed moderate or mild β-chain deficiency. The possible reason for this comparatively mild course of a β-thalassemia syndrome lies in a mild deficit in β-chain production.

Original languageEnglish (US)
Pages (from-to)57-61
Number of pages5
JournalActa Haematologica
Volume67
Issue number1
DOIs
StatePublished - Jan 1 1982
Externally publishedYes

Fingerprint

Hemoglobin A2
Fetal Hemoglobin
Thalassemia
beta-Thalassemia
Parents
Homozygote

ASJC Scopus subject areas

  • Hematology

Cite this

β-Thalassemia intermedia homozygous for normal hemoglobin A2 β-thalassemia. Study in four families. / Aksoy, M.; Bermek, E.; Almis, G.; Kutlar, Abdullah.

In: Acta Haematologica, Vol. 67, No. 1, 01.01.1982, p. 57-61.

Research output: Contribution to journalArticle

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