A collaborative study of a new antidepressant, viloxazine, in neurotic and endogenous depressives

W. Guy, T. A. Ban, Joseph Patrick McEvoy, W. M. Petrie, W. H. Wilson, J. D. Schaffer

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

In a multicenter series of trials, viloxazine was compared with imipramine, amitriptyline, doxepin and placebo in 123 neurotic and endogenous depressive inpatients and outpatients. While significant period effects reflecting improvement were obtained on the majority of efficacy variables, no significant differences were obtained among the treatment groups or depressive types. Imipramine and amitriptyline exhibited more anticholinergic adverse reactions; while, viloxazine exhibited greater CNS effects. Dizziness and nausea were much more frequent in neurotic depressives which may be related to their psychopathology.

Original languageEnglish (US)
Pages (from-to)36-42
Number of pages7
JournalUnknown Journal
Volume17
Issue number1
DOIs
StatePublished - Jan 1 1982
Externally publishedYes

Fingerprint

Viloxazine
Amitriptyline
Imipramine
Antidepressive Agents
Doxepin
Cholinergic Antagonists
Dizziness
psychopathology
Psychopathology
Nausea
Multicenter Studies
Inpatients
Outpatients
Placebos
Group
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

A collaborative study of a new antidepressant, viloxazine, in neurotic and endogenous depressives. / Guy, W.; Ban, T. A.; McEvoy, Joseph Patrick; Petrie, W. M.; Wilson, W. H.; Schaffer, J. D.

In: Unknown Journal, Vol. 17, No. 1, 01.01.1982, p. 36-42.

Research output: Contribution to journalArticle

Guy, W. ; Ban, T. A. ; McEvoy, Joseph Patrick ; Petrie, W. M. ; Wilson, W. H. ; Schaffer, J. D. / A collaborative study of a new antidepressant, viloxazine, in neurotic and endogenous depressives. In: Unknown Journal. 1982 ; Vol. 17, No. 1. pp. 36-42.
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