A Complete Guide on Crushing Tablets and/or Opening Capsules of Human Immunodeficiency Virus Medications

Sonal Patel, James William Spence, Sohini Veean, Jose Gonzales-Zamora, Jose Antonio Vazquez

Research output: Contribution to journalArticle


There are limited data regarding the ability to crush tablets or open capsules for antiretroviral agents. This lack of data is problematic when encountering patients who cannot swallow these tablets or capsules, especially for patients who are mechanically ventilated. Furthermore, many antiretroviral agents do not have an oral or intravenous solution available. The authors address this issue by reviewing all commercially available antiretroviral agents to determine whether they could crush tablets or open capsules.

Original languageEnglish (US)
Pages (from-to)214-217
Number of pages4
JournalInfectious Diseases in Clinical Practice
Issue number4
StatePublished - Jul 1 2017



  • HIV
  • antiretroviral
  • do-not-crush

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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