A non-penetrating thiol reagent mimics cytochalasin a inhibition of secretory protein synthesis

Elias K. Manavathu; Donovan des S. Thomas

doi:10.1016/0006-291X(76)90279-5

A non-penetrating thiol reagent mimics cytochalasin a inhibition of secretory protein synthesis

Elias K. Manavathu, Donovan des S. Thomas

Infectious Disease

Research output: Contribution to journal › Article

5 Scopus citations

Abstract

Mimicry of selective cytochalasin A (CA) inhibition of cellulase synthesis in the water mold Achlya by the non-penetrating thiol reagent, p-chloromercuribenzene sulphonate suggests that CA may act as a non-permeant sulphydryl reagent, and that inhibition of cellulase synthesis may be exerted via relatively superficial thiol groups in the plasma membrane.

Original language	English (US)
Pages (from-to)	280-285
Number of pages	6
Journal	Biochemical and Biophysical Research Communications
Volume	71
Issue number	1
DOIs	https://doi.org/10.1016/0006-291X(76)90279-5
State	Published - Jul 12 1976

Fingerprint

ASJC Scopus subject areas

Biophysics
Biochemistry
Molecular Biology
Cell Biology

Cite this

Manavathu, E. K., & Thomas, D. D. S. (1976). A non-penetrating thiol reagent mimics cytochalasin a inhibition of secretory protein synthesis. Biochemical and Biophysical Research Communications, 71(1), 280-285. https://doi.org/10.1016/0006-291X(76)90279-5

@article{dd44541a7d5d4ea7925040376eafad5c,

title = "A non-penetrating thiol reagent mimics cytochalasin a inhibition of secretory protein synthesis",

abstract = "Mimicry of selective cytochalasin A (CA) inhibition of cellulase synthesis in the water mold Achlya by the non-penetrating thiol reagent, p-chloromercuribenzene sulphonate suggests that CA may act as a non-permeant sulphydryl reagent, and that inhibition of cellulase synthesis may be exerted via relatively superficial thiol groups in the plasma membrane.",

author = "Manavathu, {Elias K.} and Thomas, {Donovan des S.}",

year = "1976",

month = jul,

day = "12",

doi = "10.1016/0006-291X(76)90279-5",

language = "English (US)",

volume = "71",

pages = "280--285",

journal = "Biochemical and Biophysical Research Communications",

issn = "0006-291X",

publisher = "Academic Press Inc.",

number = "1",

}

TY - JOUR

T1 - A non-penetrating thiol reagent mimics cytochalasin a inhibition of secretory protein synthesis

AU - Manavathu, Elias K.

AU - Thomas, Donovan des S.

PY - 1976/7/12

Y1 - 1976/7/12

N2 - Mimicry of selective cytochalasin A (CA) inhibition of cellulase synthesis in the water mold Achlya by the non-penetrating thiol reagent, p-chloromercuribenzene sulphonate suggests that CA may act as a non-permeant sulphydryl reagent, and that inhibition of cellulase synthesis may be exerted via relatively superficial thiol groups in the plasma membrane.

AB - Mimicry of selective cytochalasin A (CA) inhibition of cellulase synthesis in the water mold Achlya by the non-penetrating thiol reagent, p-chloromercuribenzene sulphonate suggests that CA may act as a non-permeant sulphydryl reagent, and that inhibition of cellulase synthesis may be exerted via relatively superficial thiol groups in the plasma membrane.

UR - http://www.scopus.com/inward/record.url?scp=0017083839&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0017083839&partnerID=8YFLogxK

U2 - 10.1016/0006-291X(76)90279-5

DO - 10.1016/0006-291X(76)90279-5

M3 - Article

C2 - 962920

AN - SCOPUS:0017083839

VL - 71

SP - 280

EP - 285

JO - Biochemical and Biophysical Research Communications

JF - Biochemical and Biophysical Research Communications

SN - 0006-291X

IS - 1

ER -

Access to Document

10.1016/0006-291X(76)90279-5