A non-penetrating thiol reagent mimics cytochalasin a inhibition of secretory protein synthesis

Elias K. Manavathu, Donovan des S. Thomas

Research output: Contribution to journalArticle

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Abstract

Mimicry of selective cytochalasin A (CA) inhibition of cellulase synthesis in the water mold Achlya by the non-penetrating thiol reagent, p-chloromercuribenzene sulphonate suggests that CA may act as a non-permeant sulphydryl reagent, and that inhibition of cellulase synthesis may be exerted via relatively superficial thiol groups in the plasma membrane.

Original languageEnglish (US)
Pages (from-to)280-285
Number of pages6
JournalBiochemical and Biophysical Research Communications
Volume71
Issue number1
DOIs
StatePublished - Jul 12 1976

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ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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