Abnormal ocular motor function predicts clinical diagnosis of familial ataxia

J. T. Hutton, J. W. Albrecht, M. Kuskowski, L. J. Schut

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Ocular motor performance was significantly impaired in familial ataxia patients as compared with normal controls. Ataxic patients showed prolonged saccadic latencies, longer saccadic refixation times, reduced visual tracking performance, and increased saccadic hypermetria. Cutoff values were derived and applied to 15 subjects at risk for developing familial ataxia. Three of 15 showed abnormal values in three or more of four categories of ocular motor performance. Within 3 years, all three subjects were diagnosed on clinical grounds as having familial ataxia. We concluded that ocular motor performance is impaired in familial ataxia and may prove useful for earlier diagnosis.

Original languageEnglish (US)
Pages (from-to)698-701
Number of pages4
JournalNeurology
Volume37
Issue number4
StatePublished - Jan 1 1987

Fingerprint

Ataxia
Cerebellar Ataxia
Early Diagnosis

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Hutton, J. T., Albrecht, J. W., Kuskowski, M., & Schut, L. J. (1987). Abnormal ocular motor function predicts clinical diagnosis of familial ataxia. Neurology, 37(4), 698-701.

Abnormal ocular motor function predicts clinical diagnosis of familial ataxia. / Hutton, J. T.; Albrecht, J. W.; Kuskowski, M.; Schut, L. J.

In: Neurology, Vol. 37, No. 4, 01.01.1987, p. 698-701.

Research output: Contribution to journalArticle

Hutton, JT, Albrecht, JW, Kuskowski, M & Schut, LJ 1987, 'Abnormal ocular motor function predicts clinical diagnosis of familial ataxia', Neurology, vol. 37, no. 4, pp. 698-701.
Hutton JT, Albrecht JW, Kuskowski M, Schut LJ. Abnormal ocular motor function predicts clinical diagnosis of familial ataxia. Neurology. 1987 Jan 1;37(4):698-701.
Hutton, J. T. ; Albrecht, J. W. ; Kuskowski, M. ; Schut, L. J. / Abnormal ocular motor function predicts clinical diagnosis of familial ataxia. In: Neurology. 1987 ; Vol. 37, No. 4. pp. 698-701.
@article{2563420d4e52455f8b92077bed3b1e83,
title = "Abnormal ocular motor function predicts clinical diagnosis of familial ataxia",
abstract = "Ocular motor performance was significantly impaired in familial ataxia patients as compared with normal controls. Ataxic patients showed prolonged saccadic latencies, longer saccadic refixation times, reduced visual tracking performance, and increased saccadic hypermetria. Cutoff values were derived and applied to 15 subjects at risk for developing familial ataxia. Three of 15 showed abnormal values in three or more of four categories of ocular motor performance. Within 3 years, all three subjects were diagnosed on clinical grounds as having familial ataxia. We concluded that ocular motor performance is impaired in familial ataxia and may prove useful for earlier diagnosis.",
author = "Hutton, {J. T.} and Albrecht, {J. W.} and M. Kuskowski and Schut, {L. J.}",
year = "1987",
month = "1",
day = "1",
language = "English (US)",
volume = "37",
pages = "698--701",
journal = "Neurology",
issn = "0028-3878",
publisher = "Lippincott Williams and Wilkins",
number = "4",

}

TY - JOUR

T1 - Abnormal ocular motor function predicts clinical diagnosis of familial ataxia

AU - Hutton, J. T.

AU - Albrecht, J. W.

AU - Kuskowski, M.

AU - Schut, L. J.

PY - 1987/1/1

Y1 - 1987/1/1

N2 - Ocular motor performance was significantly impaired in familial ataxia patients as compared with normal controls. Ataxic patients showed prolonged saccadic latencies, longer saccadic refixation times, reduced visual tracking performance, and increased saccadic hypermetria. Cutoff values were derived and applied to 15 subjects at risk for developing familial ataxia. Three of 15 showed abnormal values in three or more of four categories of ocular motor performance. Within 3 years, all three subjects were diagnosed on clinical grounds as having familial ataxia. We concluded that ocular motor performance is impaired in familial ataxia and may prove useful for earlier diagnosis.

AB - Ocular motor performance was significantly impaired in familial ataxia patients as compared with normal controls. Ataxic patients showed prolonged saccadic latencies, longer saccadic refixation times, reduced visual tracking performance, and increased saccadic hypermetria. Cutoff values were derived and applied to 15 subjects at risk for developing familial ataxia. Three of 15 showed abnormal values in three or more of four categories of ocular motor performance. Within 3 years, all three subjects were diagnosed on clinical grounds as having familial ataxia. We concluded that ocular motor performance is impaired in familial ataxia and may prove useful for earlier diagnosis.

UR - http://www.scopus.com/inward/record.url?scp=0023091266&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023091266&partnerID=8YFLogxK

M3 - Article

C2 - 3470630

AN - SCOPUS:0023091266

VL - 37

SP - 698

EP - 701

JO - Neurology

JF - Neurology

SN - 0028-3878

IS - 4

ER -