Accuracy of intraoperative ultrasonography in diagnosing liver metastasis from colorectal cancer

Evaluation with postoperative follow-up results

Junji Machi, Hiroharu Isomoto, Toshihiko Kurohiji, Yuichi Yamashita, Kazuo Shirouzu, Teruo Kakegawa, Bernard Sigel, Howard A. Zaren, Joaquin Sariego

Research output: Contribution to journalArticle

122 Citations (Scopus)

Abstract

The accuracy of intraoperative ultrasonography in diagnosing liver metastasis was evaluated at the time of surgery and at follow-up in 189 patients with colorectal cancers. Evaluation at the time of operation revealed that the sensitivity of intraoperative ultrasonography (93.3%) was significantly (p<0.0001) higher than that of preoperative ultrasonography (41.3%), conventional computed tomography (47.1%), and surgical exploration (66.3%). Twenty-two of 104 metastatic liver tumors were detected solely by intraoperative ultrasonography in 18 patients (9.5% of total patients). These 22 tumors were small in size (4×4 mm to 15×18 mm) and nonpalpable during operation. During the postoperative follow-up period of 18 months or more (mean 35.6 months, median 37.1 months) after colorectal surgery, liver metastases that were unrecognized during surgery appeared in 13 (6.9%) patients. Re-evaluation based on these follow-up results indicated that the sensitivity of intraoperative ultrasonography decreased to 82.3%, which was still significantly (p< 0.0005) better than that of other methods. Intraoperatiye ultrasonography was capable of identifying 18 of 31 (58.1%) patients in whom liver metastases were otherwise unrecognized at the time of operation. Intraoperative ultrasonography is more accurate in diagnosing liver metastasis than traditional screening methods, and may have a beneficial impact on the management of colorectal cancer.

Original languageEnglish (US)
Pages (from-to)551-556
Number of pages6
JournalWorld Journal of Surgery
Volume15
Issue number4
DOIs
StatePublished - Jul 1 1991

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Colorectal Neoplasms
Ultrasonography
Neoplasm Metastasis
Liver
Colorectal Surgery
Neoplasms
Tomography

ASJC Scopus subject areas

  • Surgery

Cite this

Accuracy of intraoperative ultrasonography in diagnosing liver metastasis from colorectal cancer : Evaluation with postoperative follow-up results. / Machi, Junji; Isomoto, Hiroharu; Kurohiji, Toshihiko; Yamashita, Yuichi; Shirouzu, Kazuo; Kakegawa, Teruo; Sigel, Bernard; Zaren, Howard A.; Sariego, Joaquin.

In: World Journal of Surgery, Vol. 15, No. 4, 01.07.1991, p. 551-556.

Research output: Contribution to journalArticle

Machi, J, Isomoto, H, Kurohiji, T, Yamashita, Y, Shirouzu, K, Kakegawa, T, Sigel, B, Zaren, HA & Sariego, J 1991, 'Accuracy of intraoperative ultrasonography in diagnosing liver metastasis from colorectal cancer: Evaluation with postoperative follow-up results', World Journal of Surgery, vol. 15, no. 4, pp. 551-556. https://doi.org/10.1007/BF01675662
Machi, Junji ; Isomoto, Hiroharu ; Kurohiji, Toshihiko ; Yamashita, Yuichi ; Shirouzu, Kazuo ; Kakegawa, Teruo ; Sigel, Bernard ; Zaren, Howard A. ; Sariego, Joaquin. / Accuracy of intraoperative ultrasonography in diagnosing liver metastasis from colorectal cancer : Evaluation with postoperative follow-up results. In: World Journal of Surgery. 1991 ; Vol. 15, No. 4. pp. 551-556.
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