Active surveillance for papillary thyroid microcarcinoma: New challenges and opportunities for the health care system

Grace C. Haser, R. Michael Tuttle, Henry K. Su, Eran E. Alon, Donald Bergman, Victor Bernet, Elise Brett, Rhoda Cobin, Eliza H. Dewey, Gerard Doherty, Laura L. Dos Reis, Jeffrey Harris, Joshua Klopper, Stephanie L. Lee, Robert A. Levine, Stephen J. Lepore, Ilya Likhterov, Mark A. Lupo, Josef Machac, Jeffrey I. MechanickSaral Mehra, Mira Milas, Lisa A. Orloff, Gregory Randolph, Tracey A. Revenson, Katherine J. Roberts, Douglas S. Ross, Meghan E. Rowe, Robert C. Smallridge, David J Terris, Ralph P. Tufano, Mark L. Urken

Research output: Contribution to journalReview article

25 Citations (Scopus)

Abstract

Objective: The dramatic increase in papillary thyroid carcinoma (PTC) is primarily a result of early diagnosis of small cancers. Active surveillance is a promising management strategy for papillary thyroid microcarcinomas (PTMCs). However, as this management strategy gains traction in the U.S., it is imperative that patients and clinicians be properly educated, patients be followed for life, and appropriate tools be identified to implement the strategy. Methods: We review previous active surveillance studies and the parameters used to identify patients who are good candidates for active surveillance. We also review some of the challenges to implementing active surveillance protocols in the U.S. and discuss how these might be addressed. Results: Trials of active surveillance support nonsurgical management as a viable and safe management strategy. However, numerous challenges exist, including the need for adherence to protocols, education of patients and physicians, and awareness of the impact of this strategy on patient psychology and quality of life. The Thyroid Cancer Care Collaborative (TCCC) is a portable record keeping system that can manage a mobile patient population undergoing active surveillance. Conclusion: With proper patient selection, organization, and patient support, active surveillance has the potential to be a long-term management strategy for select patients with PTMC. In order to address the challenges and opportunities for this approach to be successfully implemented in the U.S., it will be necessary to consider psychological and quality of life, cultural differences, and the patient's clinical status.

Original languageEnglish (US)
Pages (from-to)62-611
Number of pages550
JournalEndocrine Practice
Volume22
Issue number5
DOIs
StatePublished - Jan 1 2016

Fingerprint

Delivery of Health Care
Thyroid Gland
Quality of Life
Psychology
Papillary Thyroid Microcarcinoma
Traction
Patient Education
Early Detection of Cancer
Thyroid Neoplasms
Patient Selection
Organizations
Physicians
Population

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

Cite this

Haser, G. C., Tuttle, R. M., Su, H. K., Alon, E. E., Bergman, D., Bernet, V., ... Urken, M. L. (2016). Active surveillance for papillary thyroid microcarcinoma: New challenges and opportunities for the health care system. Endocrine Practice, 22(5), 62-611. https://doi.org/10.4158/EP151065.RA

Active surveillance for papillary thyroid microcarcinoma : New challenges and opportunities for the health care system. / Haser, Grace C.; Tuttle, R. Michael; Su, Henry K.; Alon, Eran E.; Bergman, Donald; Bernet, Victor; Brett, Elise; Cobin, Rhoda; Dewey, Eliza H.; Doherty, Gerard; Dos Reis, Laura L.; Harris, Jeffrey; Klopper, Joshua; Lee, Stephanie L.; Levine, Robert A.; Lepore, Stephen J.; Likhterov, Ilya; Lupo, Mark A.; Machac, Josef; Mechanick, Jeffrey I.; Mehra, Saral; Milas, Mira; Orloff, Lisa A.; Randolph, Gregory; Revenson, Tracey A.; Roberts, Katherine J.; Ross, Douglas S.; Rowe, Meghan E.; Smallridge, Robert C.; Terris, David J; Tufano, Ralph P.; Urken, Mark L.

In: Endocrine Practice, Vol. 22, No. 5, 01.01.2016, p. 62-611.

Research output: Contribution to journalReview article

Haser, GC, Tuttle, RM, Su, HK, Alon, EE, Bergman, D, Bernet, V, Brett, E, Cobin, R, Dewey, EH, Doherty, G, Dos Reis, LL, Harris, J, Klopper, J, Lee, SL, Levine, RA, Lepore, SJ, Likhterov, I, Lupo, MA, Machac, J, Mechanick, JI, Mehra, S, Milas, M, Orloff, LA, Randolph, G, Revenson, TA, Roberts, KJ, Ross, DS, Rowe, ME, Smallridge, RC, Terris, DJ, Tufano, RP & Urken, ML 2016, 'Active surveillance for papillary thyroid microcarcinoma: New challenges and opportunities for the health care system', Endocrine Practice, vol. 22, no. 5, pp. 62-611. https://doi.org/10.4158/EP151065.RA
Haser, Grace C. ; Tuttle, R. Michael ; Su, Henry K. ; Alon, Eran E. ; Bergman, Donald ; Bernet, Victor ; Brett, Elise ; Cobin, Rhoda ; Dewey, Eliza H. ; Doherty, Gerard ; Dos Reis, Laura L. ; Harris, Jeffrey ; Klopper, Joshua ; Lee, Stephanie L. ; Levine, Robert A. ; Lepore, Stephen J. ; Likhterov, Ilya ; Lupo, Mark A. ; Machac, Josef ; Mechanick, Jeffrey I. ; Mehra, Saral ; Milas, Mira ; Orloff, Lisa A. ; Randolph, Gregory ; Revenson, Tracey A. ; Roberts, Katherine J. ; Ross, Douglas S. ; Rowe, Meghan E. ; Smallridge, Robert C. ; Terris, David J ; Tufano, Ralph P. ; Urken, Mark L. / Active surveillance for papillary thyroid microcarcinoma : New challenges and opportunities for the health care system. In: Endocrine Practice. 2016 ; Vol. 22, No. 5. pp. 62-611.
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abstract = "Objective: The dramatic increase in papillary thyroid carcinoma (PTC) is primarily a result of early diagnosis of small cancers. Active surveillance is a promising management strategy for papillary thyroid microcarcinomas (PTMCs). However, as this management strategy gains traction in the U.S., it is imperative that patients and clinicians be properly educated, patients be followed for life, and appropriate tools be identified to implement the strategy. Methods: We review previous active surveillance studies and the parameters used to identify patients who are good candidates for active surveillance. We also review some of the challenges to implementing active surveillance protocols in the U.S. and discuss how these might be addressed. Results: Trials of active surveillance support nonsurgical management as a viable and safe management strategy. However, numerous challenges exist, including the need for adherence to protocols, education of patients and physicians, and awareness of the impact of this strategy on patient psychology and quality of life. The Thyroid Cancer Care Collaborative (TCCC) is a portable record keeping system that can manage a mobile patient population undergoing active surveillance. Conclusion: With proper patient selection, organization, and patient support, active surveillance has the potential to be a long-term management strategy for select patients with PTMC. In order to address the challenges and opportunities for this approach to be successfully implemented in the U.S., it will be necessary to consider psychological and quality of life, cultural differences, and the patient's clinical status.",
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T1 - Active surveillance for papillary thyroid microcarcinoma

T2 - New challenges and opportunities for the health care system

AU - Haser, Grace C.

AU - Tuttle, R. Michael

AU - Su, Henry K.

AU - Alon, Eran E.

AU - Bergman, Donald

AU - Bernet, Victor

AU - Brett, Elise

AU - Cobin, Rhoda

AU - Dewey, Eliza H.

AU - Doherty, Gerard

AU - Dos Reis, Laura L.

AU - Harris, Jeffrey

AU - Klopper, Joshua

AU - Lee, Stephanie L.

AU - Levine, Robert A.

AU - Lepore, Stephen J.

AU - Likhterov, Ilya

AU - Lupo, Mark A.

AU - Machac, Josef

AU - Mechanick, Jeffrey I.

AU - Mehra, Saral

AU - Milas, Mira

AU - Orloff, Lisa A.

AU - Randolph, Gregory

AU - Revenson, Tracey A.

AU - Roberts, Katherine J.

AU - Ross, Douglas S.

AU - Rowe, Meghan E.

AU - Smallridge, Robert C.

AU - Terris, David J

AU - Tufano, Ralph P.

AU - Urken, Mark L.

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