Aging and the muscle-bone relationship

Susan A. Novotny, Gordon L. Warren, Mark W. Hamrick

Research output: Contribution to journalReview article

33 Scopus citations


Aging-induced declines in muscle size and quality are thought to contribute to catabolic alterations in bone, but changes in bone with age also profoundly alter its response to muscle-derived stimuli. This review provides an overview of some of the alterations that occur in muscle and bone with aging, and discusses the cellular and molecular mechanisms that may impact these ageassociated changes.

Original languageEnglish (US)
Pages (from-to)8-16
Number of pages9
Issue number1
StatePublished - Jan 1 2015


ASJC Scopus subject areas

  • Physiology

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