Alcohol dependence and hospitalization in schizophrenia

Lori B. Gerding, Lawrence A. Labbate, Michael O. Measom, Alberto B. Santos, George W. Arana

Research output: Contribution to journalArticlepeer-review

42 Scopus citations


Treatment of schizophrenia is often complicated by substance abuse. We report here findings of a retrospective study evaluating readmission rates of patients meeting DSM IV criteria comorbid for schizophrenia and alcohol or drug dependence treated with depot haloperidol or fluphenazine over a 2-year period. During the study period, 14 of the 26 (54%) male veteran patients were admitted to the VAMC, Charleston; 46% of patients met criteria for alcohol, marijuana or cocaine dependence. Patients with alcohol dependence appeared to be at highest risk for hospital admission (p<0.05). Moreover, patients with alcohol dependence had longer hospital stays (p<0.05) than patients without alcohol dependence. Marijuana or cocaine dependence was slightly, but not statistically more common among admitted patients. Marijuana or cocaine dependence did not predict length of stay or number of admissions. Alcohol dependence may be an important factor in schizophrenic exacerbation, and may be an important target for treatment.

Original languageEnglish (US)
Pages (from-to)71-75
Number of pages5
JournalSchizophrenia Research
Issue number1
StatePublished - Jul 27 1999


  • Alcohol dependence
  • Medication compliance
  • Schizophrenia

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry


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