Altered in vitro immune response to hypoxia-treated normal peritoneal fibroblasts

Zeynep Alpay, Melike Özgönenel, Süreyya Savaşan, Steven Buck, Ghassan M. Saed, Michael P. Diamond

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Hypoxia treatment of normal peritoneal fibroblasts results in alterations that are characteristic for fibroblasts obtained from postoperative peritoneal adhesion tissue. In this study, we have shown that hypoxia treatment enhances normal peritoneal fibroblast elimination by lymphokine-activated killer cells to the level of adhesion tissue fibroblasts, suggesting a pivotal role of hypoxia in the adhesion development.

Original languageEnglish (US)
Pages (from-to)426-429
Number of pages4
JournalFertility and sterility
Volume87
Issue number2
DOIs
StatePublished - Feb 1 2007
Externally publishedYes

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

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