Altitude illness

Update on prevention and treatment

Richard P. Eide, Chad Alan Asplund

Research output: Contribution to journalReview article

21 Citations (Scopus)

Abstract

Altitude illness is a broad category of disease encompassing acute mountain sickness (AMS), high-altitude cerebral edema (HACE), and highaltitude pulmonary edema (HAPE) that can affect persons who travel to altitude without adequate acclimatization. Initial symptoms of AMS and the more serious HACE or HAPE can be subtle, and it is important that the practitioner be able to recognize and differentiate between these diagnoses because they can progress rapidly and be fatal if untreated. There are well-established criteria and many proven therapies both for prophylaxis and treatment of altitude illness; however, despite intense research efforts, the specific mechanisms of these complex diseases remain elusive. Adequate acclimatization via controlled ascent remains the most important factor in preventing altitude illness, although prophylactic pharmacotherapy also may be useful. Rapid descent remains the most important treatment factor, although treatment at altitude with various therapies is possible for mild cases with adequate resources.

Original languageEnglish (US)
Pages (from-to)124-130
Number of pages7
JournalCurrent Sports Medicine Reports
Volume11
Issue number3
DOIs
StatePublished - May 1 2012

Fingerprint

Altitude Sickness
Acclimatization
Brain Edema
Pulmonary Edema
Therapeutics
Acute Disease
Drug Therapy
Research

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Public Health, Environmental and Occupational Health

Cite this

Altitude illness : Update on prevention and treatment. / Eide, Richard P.; Asplund, Chad Alan.

In: Current Sports Medicine Reports, Vol. 11, No. 3, 01.05.2012, p. 124-130.

Research output: Contribution to journalReview article

Eide, Richard P. ; Asplund, Chad Alan. / Altitude illness : Update on prevention and treatment. In: Current Sports Medicine Reports. 2012 ; Vol. 11, No. 3. pp. 124-130.
@article{ba80aa35b17240eba97976b5ebf4bc87,
title = "Altitude illness: Update on prevention and treatment",
abstract = "Altitude illness is a broad category of disease encompassing acute mountain sickness (AMS), high-altitude cerebral edema (HACE), and highaltitude pulmonary edema (HAPE) that can affect persons who travel to altitude without adequate acclimatization. Initial symptoms of AMS and the more serious HACE or HAPE can be subtle, and it is important that the practitioner be able to recognize and differentiate between these diagnoses because they can progress rapidly and be fatal if untreated. There are well-established criteria and many proven therapies both for prophylaxis and treatment of altitude illness; however, despite intense research efforts, the specific mechanisms of these complex diseases remain elusive. Adequate acclimatization via controlled ascent remains the most important factor in preventing altitude illness, although prophylactic pharmacotherapy also may be useful. Rapid descent remains the most important treatment factor, although treatment at altitude with various therapies is possible for mild cases with adequate resources.",
author = "Eide, {Richard P.} and Asplund, {Chad Alan}",
year = "2012",
month = "5",
day = "1",
doi = "10.1249/JSR.0b013e3182563e7a",
language = "English (US)",
volume = "11",
pages = "124--130",
journal = "Current Sports Medicine Reports",
issn = "1537-890X",
publisher = "Lippincott Williams and Wilkins",
number = "3",

}

TY - JOUR

T1 - Altitude illness

T2 - Update on prevention and treatment

AU - Eide, Richard P.

AU - Asplund, Chad Alan

PY - 2012/5/1

Y1 - 2012/5/1

N2 - Altitude illness is a broad category of disease encompassing acute mountain sickness (AMS), high-altitude cerebral edema (HACE), and highaltitude pulmonary edema (HAPE) that can affect persons who travel to altitude without adequate acclimatization. Initial symptoms of AMS and the more serious HACE or HAPE can be subtle, and it is important that the practitioner be able to recognize and differentiate between these diagnoses because they can progress rapidly and be fatal if untreated. There are well-established criteria and many proven therapies both for prophylaxis and treatment of altitude illness; however, despite intense research efforts, the specific mechanisms of these complex diseases remain elusive. Adequate acclimatization via controlled ascent remains the most important factor in preventing altitude illness, although prophylactic pharmacotherapy also may be useful. Rapid descent remains the most important treatment factor, although treatment at altitude with various therapies is possible for mild cases with adequate resources.

AB - Altitude illness is a broad category of disease encompassing acute mountain sickness (AMS), high-altitude cerebral edema (HACE), and highaltitude pulmonary edema (HAPE) that can affect persons who travel to altitude without adequate acclimatization. Initial symptoms of AMS and the more serious HACE or HAPE can be subtle, and it is important that the practitioner be able to recognize and differentiate between these diagnoses because they can progress rapidly and be fatal if untreated. There are well-established criteria and many proven therapies both for prophylaxis and treatment of altitude illness; however, despite intense research efforts, the specific mechanisms of these complex diseases remain elusive. Adequate acclimatization via controlled ascent remains the most important factor in preventing altitude illness, although prophylactic pharmacotherapy also may be useful. Rapid descent remains the most important treatment factor, although treatment at altitude with various therapies is possible for mild cases with adequate resources.

UR - http://www.scopus.com/inward/record.url?scp=84863613860&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84863613860&partnerID=8YFLogxK

U2 - 10.1249/JSR.0b013e3182563e7a

DO - 10.1249/JSR.0b013e3182563e7a

M3 - Review article

VL - 11

SP - 124

EP - 130

JO - Current Sports Medicine Reports

JF - Current Sports Medicine Reports

SN - 1537-890X

IS - 3

ER -