An evaluation of a 2% erythromycin ointment in the topical therapy of acne vulgaris

Jack L. Lesher, Dan K. Chalker, J. Graham Smith, Lyn C. Guenther, Charles N. Ellis, John J. Voorhees, Alan R. Shalita, Harry C. Klauda

Research output: Contribution to journalLetterpeer-review

32 Scopus citations

Abstract

Two hundred eight patients completed a 12-week, multicenter, double-blind, controlled study comparing a 2% erythromycin ointment to its vehicle. Patients were evaluated by inflammatory lesion counts and Cook acne severity grade at the initial visit and at weeks 2, 4, 8, 10, and 12. The 2% erythromycin ointment proved to be statistically more effective than the vehicle in reducing lesion counts and acne severity grade at weeks 4, 8, 10, and 12. The ointment caused few side effects and was well tolerated by most patients.

Original languageEnglish (US)
Pages (from-to)526-531
Number of pages6
JournalJournal of the American Academy of Dermatology
Volume12
Issue number3
DOIs
StatePublished - 1985

ASJC Scopus subject areas

  • Dermatology

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