Biological effects of blue light from dental curing units

John C. Wataha, Petra E. Lockwood, Jill B. Lewis, Frederick Rueggeberg, Regina L W Messer

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

The effects of dental photocuring blue light sources on the cellular function of fibroblasts were analyzed. Mouse fibroblasts were exposed to light from dental photocuring units for clinically relevant durations, with total energy exposures ranging from 1.3 to 60 J/cm2. The temperature rise of the cell-culture medium was measured to assess any possible effect from temperature increases, and cellular function was assessed by succinic dehydrogenase (SDH) activity of mitochondria. The results indicate that the photocuring sources pose some risk of disrupting cellular function in vivo.

Original languageEnglish (US)
Pages (from-to)150-157
Number of pages8
JournalDental Materials
Volume20
Issue number2
DOIs
StatePublished - Feb 1 2004

Fingerprint

Dental Curing Lights
Curing
Tooth
Fibroblasts
Light
Temperature
Succinate Dehydrogenase
Culture Media
Mitochondria
Cell Culture Techniques
Cell culture
Light sources

Keywords

  • Blue light
  • Cell-culture
  • Cytotoxicity
  • Fibroblasts
  • Mitochondrial activity
  • Photocuring
  • Succinic dehydrogenase

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Biological effects of blue light from dental curing units. / Wataha, John C.; Lockwood, Petra E.; Lewis, Jill B.; Rueggeberg, Frederick; Messer, Regina L W.

In: Dental Materials, Vol. 20, No. 2, 01.02.2004, p. 150-157.

Research output: Contribution to journalArticle

Wataha, John C. ; Lockwood, Petra E. ; Lewis, Jill B. ; Rueggeberg, Frederick ; Messer, Regina L W. / Biological effects of blue light from dental curing units. In: Dental Materials. 2004 ; Vol. 20, No. 2. pp. 150-157.
@article{75f9f27bcde94b878c17a081ecf87e40,
title = "Biological effects of blue light from dental curing units",
abstract = "The effects of dental photocuring blue light sources on the cellular function of fibroblasts were analyzed. Mouse fibroblasts were exposed to light from dental photocuring units for clinically relevant durations, with total energy exposures ranging from 1.3 to 60 J/cm2. The temperature rise of the cell-culture medium was measured to assess any possible effect from temperature increases, and cellular function was assessed by succinic dehydrogenase (SDH) activity of mitochondria. The results indicate that the photocuring sources pose some risk of disrupting cellular function in vivo.",
keywords = "Blue light, Cell-culture, Cytotoxicity, Fibroblasts, Mitochondrial activity, Photocuring, Succinic dehydrogenase",
author = "Wataha, {John C.} and Lockwood, {Petra E.} and Lewis, {Jill B.} and Frederick Rueggeberg and Messer, {Regina L W}",
year = "2004",
month = "2",
day = "1",
doi = "10.1016/S0109-5641(03)00086-1",
language = "English (US)",
volume = "20",
pages = "150--157",
journal = "Dental Materials",
issn = "0109-5641",
publisher = "Elsevier Science",
number = "2",

}

TY - JOUR

T1 - Biological effects of blue light from dental curing units

AU - Wataha, John C.

AU - Lockwood, Petra E.

AU - Lewis, Jill B.

AU - Rueggeberg, Frederick

AU - Messer, Regina L W

PY - 2004/2/1

Y1 - 2004/2/1

N2 - The effects of dental photocuring blue light sources on the cellular function of fibroblasts were analyzed. Mouse fibroblasts were exposed to light from dental photocuring units for clinically relevant durations, with total energy exposures ranging from 1.3 to 60 J/cm2. The temperature rise of the cell-culture medium was measured to assess any possible effect from temperature increases, and cellular function was assessed by succinic dehydrogenase (SDH) activity of mitochondria. The results indicate that the photocuring sources pose some risk of disrupting cellular function in vivo.

AB - The effects of dental photocuring blue light sources on the cellular function of fibroblasts were analyzed. Mouse fibroblasts were exposed to light from dental photocuring units for clinically relevant durations, with total energy exposures ranging from 1.3 to 60 J/cm2. The temperature rise of the cell-culture medium was measured to assess any possible effect from temperature increases, and cellular function was assessed by succinic dehydrogenase (SDH) activity of mitochondria. The results indicate that the photocuring sources pose some risk of disrupting cellular function in vivo.

KW - Blue light

KW - Cell-culture

KW - Cytotoxicity

KW - Fibroblasts

KW - Mitochondrial activity

KW - Photocuring

KW - Succinic dehydrogenase

UR - http://www.scopus.com/inward/record.url?scp=0347541006&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0347541006&partnerID=8YFLogxK

U2 - 10.1016/S0109-5641(03)00086-1

DO - 10.1016/S0109-5641(03)00086-1

M3 - Article

VL - 20

SP - 150

EP - 157

JO - Dental Materials

JF - Dental Materials

SN - 0109-5641

IS - 2

ER -