Biological effects of blue light from dental curing units

John C. Wataha; Petra E. Lockwood; Jill B. Lewis; Frederick A. Rueggeberg; Regina L.W. Messer

doi:10.1016/S0109-5641(03)00086-1

Biological effects of blue light from dental curing units

John C. Wataha, Petra E. Lockwood, Jill B. Lewis, Frederick A. Rueggeberg, Regina L.W. Messer

Research output: Contribution to journal › Article › peer-review

57 Scopus citations

Abstract

The effects of dental photocuring blue light sources on the cellular function of fibroblasts were analyzed. Mouse fibroblasts were exposed to light from dental photocuring units for clinically relevant durations, with total energy exposures ranging from 1.3 to 60 J/cm². The temperature rise of the cell-culture medium was measured to assess any possible effect from temperature increases, and cellular function was assessed by succinic dehydrogenase (SDH) activity of mitochondria. The results indicate that the photocuring sources pose some risk of disrupting cellular function in vivo.

Original language	English (US)
Pages (from-to)	150-157
Number of pages	8
Journal	Dental Materials
Volume	20
Issue number	2
DOIs	https://doi.org/10.1016/S0109-5641(03)00086-1
State	Published - Feb 1 2004

Keywords

Blue light
Cell-culture
Cytotoxicity
Fibroblasts
Mitochondrial activity
Photocuring
Succinic dehydrogenase

ASJC Scopus subject areas

Materials Science(all)
Dentistry(all)
Mechanics of Materials

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title = "Biological effects of blue light from dental curing units",

abstract = "The effects of dental photocuring blue light sources on the cellular function of fibroblasts were analyzed. Mouse fibroblasts were exposed to light from dental photocuring units for clinically relevant durations, with total energy exposures ranging from 1.3 to 60 J/cm2. The temperature rise of the cell-culture medium was measured to assess any possible effect from temperature increases, and cellular function was assessed by succinic dehydrogenase (SDH) activity of mitochondria. The results indicate that the photocuring sources pose some risk of disrupting cellular function in vivo.",

keywords = "Blue light, Cell-culture, Cytotoxicity, Fibroblasts, Mitochondrial activity, Photocuring, Succinic dehydrogenase",

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T1 - Biological effects of blue light from dental curing units

AU - Wataha, John C.

AU - Lockwood, Petra E.

AU - Lewis, Jill B.

AU - Rueggeberg, Frederick A.

AU - Messer, Regina L.W.

PY - 2004/2/1

Y1 - 2004/2/1

N2 - The effects of dental photocuring blue light sources on the cellular function of fibroblasts were analyzed. Mouse fibroblasts were exposed to light from dental photocuring units for clinically relevant durations, with total energy exposures ranging from 1.3 to 60 J/cm2. The temperature rise of the cell-culture medium was measured to assess any possible effect from temperature increases, and cellular function was assessed by succinic dehydrogenase (SDH) activity of mitochondria. The results indicate that the photocuring sources pose some risk of disrupting cellular function in vivo.

AB - The effects of dental photocuring blue light sources on the cellular function of fibroblasts were analyzed. Mouse fibroblasts were exposed to light from dental photocuring units for clinically relevant durations, with total energy exposures ranging from 1.3 to 60 J/cm2. The temperature rise of the cell-culture medium was measured to assess any possible effect from temperature increases, and cellular function was assessed by succinic dehydrogenase (SDH) activity of mitochondria. The results indicate that the photocuring sources pose some risk of disrupting cellular function in vivo.

KW - Blue light

KW - Cell-culture

KW - Cytotoxicity

KW - Fibroblasts

KW - Mitochondrial activity

KW - Photocuring

KW - Succinic dehydrogenase

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JO - Dental Materials

JF - Dental Materials

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Biological effects of blue light from dental curing units

Abstract

Keywords

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