Biomarkers of endometriosis

Essam El Din R. Othman, Daniela Hornung, Ayman Al-Hendy

Research output: Contribution to journalReview article

15 Scopus citations

Abstract

Background: Diagnosis of endometriosis is surgical through laparoscopy, which is invasive, costly and associated with potential complications. Objectives: A non-invasive test for diagnosis of endometriosis will focus the use of laparoscopy on women who are highly suspected of having endometriosis. This review includes studies about different biomarkers for endometriosis and their potential for the non-surgical diagnosis of this disease. Methods: This review covers studies that investigated different biomarkers in blood or endometrium. Studies that identified definite cutoff points and evaluated the diagnostic performance of the biomarker as a blood test for endometriosis are focused on. Results/conclusions: Some of the markers investigated showed a good specificity, none of them showed a high sensitivity. More multi-center studies involving larger numbers of patients are required to identify the most useful biomarker.

Original languageEnglish (US)
Pages (from-to)741-752
Number of pages12
JournalExpert Opinion on Medical Diagnostics
Volume2
Issue number7
DOIs
StatePublished - Jul 1 2008

Keywords

  • Diagnosis
  • Endometriosis
  • Markers
  • Non-surgical

ASJC Scopus subject areas

  • Biomedical Engineering
  • Molecular Medicine
  • Biochemistry, medical

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    Othman, E. E. D. R., Hornung, D., & Al-Hendy, A. (2008). Biomarkers of endometriosis. Expert Opinion on Medical Diagnostics, 2(7), 741-752. https://doi.org/10.1517/17530059.2.7.741