Bipolar affective disorder prior to the onset of multiple sclerosis

M. Hutchinson, J. Stack, P. Buckley

Research output: Contribution to journalArticlepeer-review

37 Scopus citations


The frequent association of affective disorder and multiple sclerosis raises important aetiological and clinical considerations. Reported here are seven patients who presented with symptoms of multiple sclerosis and who had a preceding history of bipolar affective disorder. The hypothesis that bipolar illness may be the initial manifestation of multiple sclerosis is discussed with reference to relevant clinical and epidemiological research on the topic. 1993 Blackwell Munksgaard

Original languageEnglish (US)
Pages (from-to)388-393
Number of pages6
JournalActa Neurologica Scandinavica
Issue number6
StatePublished - Dec 1993
Externally publishedYes


  • bipolar affective disorder
  • multiple sclerosis

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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