Blocking Bone Loss with L-BAIBA

Research output: Contribution to journalShort surveypeer-review

Abstract

Osteocytes are cells nested within the mineralized bone matrix that play a key role in maintaining bone mass. New findings in Cell Reports show that β-aminoisobutyric acid (L-BAIBA), a metabolite secreted from muscle, promotes osteocyte survival under oxidative stress. This discovery reveals a novel mechanism linking muscle activity to skeletal health.

Original languageEnglish (US)
Pages (from-to)284-286
Number of pages3
JournalTrends in Endocrinology and Metabolism
Volume29
Issue number5
DOIs
StatePublished - May 1 2018

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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