Blocking Bone Loss with L-BAIBA

Research output: Contribution to journalShort survey

Abstract

Osteocytes are cells nested within the mineralized bone matrix that play a key role in maintaining bone mass. New findings in Cell Reports show that β-aminoisobutyric acid (L-BAIBA), a metabolite secreted from muscle, promotes osteocyte survival under oxidative stress. This discovery reveals a novel mechanism linking muscle activity to skeletal health.

Original languageEnglish (US)
Pages (from-to)284-286
Number of pages3
JournalTrends in Endocrinology and Metabolism
Volume29
Issue number5
DOIs
StatePublished - May 1 2018

Fingerprint

Osteocytes
Aminoisobutyric Acids
Bone and Bones
Muscles
Bone Matrix
Oxidative Stress
Health

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

Cite this

Blocking Bone Loss with L-BAIBA. / Hamrick, Mark W; McGee Lawrence, Meghan Elizabeth.

In: Trends in Endocrinology and Metabolism, Vol. 29, No. 5, 01.05.2018, p. 284-286.

Research output: Contribution to journalShort survey

@article{32490a895fb44ee688c55932b724c934,
title = "Blocking Bone Loss with L-BAIBA",
abstract = "Osteocytes are cells nested within the mineralized bone matrix that play a key role in maintaining bone mass. New findings in Cell Reports show that β-aminoisobutyric acid (L-BAIBA), a metabolite secreted from muscle, promotes osteocyte survival under oxidative stress. This discovery reveals a novel mechanism linking muscle activity to skeletal health.",
author = "Hamrick, {Mark W} and {McGee Lawrence}, {Meghan Elizabeth}",
year = "2018",
month = "5",
day = "1",
doi = "10.1016/j.tem.2018.03.005",
language = "English (US)",
volume = "29",
pages = "284--286",
journal = "Trends in Endocrinology and Metabolism",
issn = "1043-2760",
publisher = "Elsevier Inc.",
number = "5",

}

TY - JOUR

T1 - Blocking Bone Loss with L-BAIBA

AU - Hamrick, Mark W

AU - McGee Lawrence, Meghan Elizabeth

PY - 2018/5/1

Y1 - 2018/5/1

N2 - Osteocytes are cells nested within the mineralized bone matrix that play a key role in maintaining bone mass. New findings in Cell Reports show that β-aminoisobutyric acid (L-BAIBA), a metabolite secreted from muscle, promotes osteocyte survival under oxidative stress. This discovery reveals a novel mechanism linking muscle activity to skeletal health.

AB - Osteocytes are cells nested within the mineralized bone matrix that play a key role in maintaining bone mass. New findings in Cell Reports show that β-aminoisobutyric acid (L-BAIBA), a metabolite secreted from muscle, promotes osteocyte survival under oxidative stress. This discovery reveals a novel mechanism linking muscle activity to skeletal health.

UR - http://www.scopus.com/inward/record.url?scp=85044305349&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85044305349&partnerID=8YFLogxK

U2 - 10.1016/j.tem.2018.03.005

DO - 10.1016/j.tem.2018.03.005

M3 - Short survey

C2 - 29573947

AN - SCOPUS:85044305349

VL - 29

SP - 284

EP - 286

JO - Trends in Endocrinology and Metabolism

JF - Trends in Endocrinology and Metabolism

SN - 1043-2760

IS - 5

ER -