TY - JOUR
T1 - Blocking Bone Loss with L-BAIBA
AU - Hamrick, Mark W
AU - McGee Lawrence, Meghan Elizabeth
PY - 2018/5/1
Y1 - 2018/5/1
N2 - Osteocytes are cells nested within the mineralized bone matrix that play a key role in maintaining bone mass. New findings in Cell Reports show that β-aminoisobutyric acid (L-BAIBA), a metabolite secreted from muscle, promotes osteocyte survival under oxidative stress. This discovery reveals a novel mechanism linking muscle activity to skeletal health.
AB - Osteocytes are cells nested within the mineralized bone matrix that play a key role in maintaining bone mass. New findings in Cell Reports show that β-aminoisobutyric acid (L-BAIBA), a metabolite secreted from muscle, promotes osteocyte survival under oxidative stress. This discovery reveals a novel mechanism linking muscle activity to skeletal health.
UR - http://www.scopus.com/inward/record.url?scp=85044305349&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85044305349&partnerID=8YFLogxK
U2 - 10.1016/j.tem.2018.03.005
DO - 10.1016/j.tem.2018.03.005
M3 - Short survey
C2 - 29573947
AN - SCOPUS:85044305349
SN - 1043-2760
VL - 29
SP - 284
EP - 286
JO - Trends in Endocrinology and Metabolism
JF - Trends in Endocrinology and Metabolism
IS - 5
ER -