CHARACTERIZATION OF GLYCOSPHINGOLIPIDS BY FABMS.

Mark E. Hemling, R. Donald Sedgwick, Kenneth L. Rinehart, Robert K Yu

Research output: Contribution to journalConference article

Abstract

The growing interest in the diverse biological functions of cell membrane glycosphingolipids (GSL's) as cell surface antigens, cell-cell recognition sites, and receptors for a variety of signal molecules has prompted the constant search for new procedures for their structural analysis. Mass spectrometry, because of its high sensitivity and speed, has always figured prominently in this regard. This paper presents detailed systematic analysis of a number of GSL's of increasing complexity and their ceramides, using FAB mass spectrometry. High resolution measurements and linked scans are used to confirm fragmentations. Matrix requirements and homologous mixture analysis are also discussed.

Original languageEnglish (US)
Pages (from-to)811-812
Number of pages2
JournalAnnual Conference on Mass Spectrometry and Allied Topics
StatePublished - Dec 1 1984
Externally publishedYes

Fingerprint

Mass spectrometry
Ceramides
Cell membranes
Antigens
Structural analysis
Molecules

ASJC Scopus subject areas

  • Engineering(all)

Cite this

CHARACTERIZATION OF GLYCOSPHINGOLIPIDS BY FABMS. / Hemling, Mark E.; Sedgwick, R. Donald; Rinehart, Kenneth L.; Yu, Robert K.

In: Annual Conference on Mass Spectrometry and Allied Topics, 01.12.1984, p. 811-812.

Research output: Contribution to journalConference article

Hemling, Mark E. ; Sedgwick, R. Donald ; Rinehart, Kenneth L. ; Yu, Robert K. / CHARACTERIZATION OF GLYCOSPHINGOLIPIDS BY FABMS. In: Annual Conference on Mass Spectrometry and Allied Topics. 1984 ; pp. 811-812.
@article{56f61b5bb827496d8635f0fc0fe82c00,
title = "CHARACTERIZATION OF GLYCOSPHINGOLIPIDS BY FABMS.",
abstract = "The growing interest in the diverse biological functions of cell membrane glycosphingolipids (GSL's) as cell surface antigens, cell-cell recognition sites, and receptors for a variety of signal molecules has prompted the constant search for new procedures for their structural analysis. Mass spectrometry, because of its high sensitivity and speed, has always figured prominently in this regard. This paper presents detailed systematic analysis of a number of GSL's of increasing complexity and their ceramides, using FAB mass spectrometry. High resolution measurements and linked scans are used to confirm fragmentations. Matrix requirements and homologous mixture analysis are also discussed.",
author = "Hemling, {Mark E.} and Sedgwick, {R. Donald} and Rinehart, {Kenneth L.} and Yu, {Robert K}",
year = "1984",
month = "12",
day = "1",
language = "English (US)",
pages = "811--812",
journal = "Annual Conference on Mass Spectrometry and Allied Topics",
issn = "0739-5817",

}

TY - JOUR

T1 - CHARACTERIZATION OF GLYCOSPHINGOLIPIDS BY FABMS.

AU - Hemling, Mark E.

AU - Sedgwick, R. Donald

AU - Rinehart, Kenneth L.

AU - Yu, Robert K

PY - 1984/12/1

Y1 - 1984/12/1

N2 - The growing interest in the diverse biological functions of cell membrane glycosphingolipids (GSL's) as cell surface antigens, cell-cell recognition sites, and receptors for a variety of signal molecules has prompted the constant search for new procedures for their structural analysis. Mass spectrometry, because of its high sensitivity and speed, has always figured prominently in this regard. This paper presents detailed systematic analysis of a number of GSL's of increasing complexity and their ceramides, using FAB mass spectrometry. High resolution measurements and linked scans are used to confirm fragmentations. Matrix requirements and homologous mixture analysis are also discussed.

AB - The growing interest in the diverse biological functions of cell membrane glycosphingolipids (GSL's) as cell surface antigens, cell-cell recognition sites, and receptors for a variety of signal molecules has prompted the constant search for new procedures for their structural analysis. Mass spectrometry, because of its high sensitivity and speed, has always figured prominently in this regard. This paper presents detailed systematic analysis of a number of GSL's of increasing complexity and their ceramides, using FAB mass spectrometry. High resolution measurements and linked scans are used to confirm fragmentations. Matrix requirements and homologous mixture analysis are also discussed.

UR - http://www.scopus.com/inward/record.url?scp=0021562188&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021562188&partnerID=8YFLogxK

M3 - Conference article

SP - 811

EP - 812

JO - Annual Conference on Mass Spectrometry and Allied Topics

JF - Annual Conference on Mass Spectrometry and Allied Topics

SN - 0739-5817

ER -