Complications of preoperative embolization of cerebral arteriovenous malformations

Christopher L. Taylor, Kim Dutton, George Rappard, G. Lee Pride, Robert Replogle, Phillip D. Purdy, Jonathan White, Cole A. Giller, Thomas A. Kopitnik, Duke S. Samson

Research output: Contribution to journalReview article

127 Citations (Scopus)

Abstract

Object. Preoperative embolization is viewed by the authors as a useful adjunct in the surgical management of cerebral arteriovenous malformations (AVMs). This study was performed to determine the rate of significant complication in patients undergoing this procedure. Methods. Demographic, anatomical, and procedure data were collected prospectively. The treating physician reported complications. In addition, a review of medical records including procedure reports, operative reports, and discharge summaries was performed. Univariate statistical analysis was performed to determine if any of the variables was predictive of a poor outcome of embolization (death or permanent neurological deficit). Endovascular procedures for embolization were performed 339 times in 201 patients during an 11-year period. Female patients comprised 53.7% of the study group and 85.6% of the AVMs were supratentorial. Embolization was performed using polyvinyl alcohol particles, N-butyl cyanoacrylate, detachable coils, and/or the liquid polymer Onyx. Analyzed by procedure, a poor result of embolization occurred in 7.7%. Analyzed by patient, 11% died or had a permanent neurological deficit as a result of the embolization. None of the demographic, anatomical, or procedure variables identified were predictive of a poor outcome. Conclusions. Preoperative embolization may gradually reduce flow to an AVM, reduce intraoperative blood loss, and reduce operative time. The risks of this procedure, however, are not insignificant and must be considered in planning treatment for patients with AVMs.

Original languageEnglish (US)
Pages (from-to)810-812
Number of pages3
JournalJournal of Neurosurgery
Volume100
Issue number5
DOIs
StatePublished - Jan 1 2004
Externally publishedYes

Fingerprint

Intracranial Arteriovenous Malformations
Arteriovenous Malformations
Demography
Enbucrilate
Polyvinyl Alcohol
Endovascular Procedures
Operative Surgical Procedures
Operative Time
Medical Records
Polymers
Physicians

Keywords

  • Arteriovenous malformation
  • Brain
  • Embolization
  • Endovascular therapy
  • Outcome analysis

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Cite this

Taylor, C. L., Dutton, K., Rappard, G., Pride, G. L., Replogle, R., Purdy, P. D., ... Samson, D. S. (2004). Complications of preoperative embolization of cerebral arteriovenous malformations. Journal of Neurosurgery, 100(5), 810-812. https://doi.org/10.3171/jns.2004.100.5.0810

Complications of preoperative embolization of cerebral arteriovenous malformations. / Taylor, Christopher L.; Dutton, Kim; Rappard, George; Pride, G. Lee; Replogle, Robert; Purdy, Phillip D.; White, Jonathan; Giller, Cole A.; Kopitnik, Thomas A.; Samson, Duke S.

In: Journal of Neurosurgery, Vol. 100, No. 5, 01.01.2004, p. 810-812.

Research output: Contribution to journalReview article

Taylor, CL, Dutton, K, Rappard, G, Pride, GL, Replogle, R, Purdy, PD, White, J, Giller, CA, Kopitnik, TA & Samson, DS 2004, 'Complications of preoperative embolization of cerebral arteriovenous malformations', Journal of Neurosurgery, vol. 100, no. 5, pp. 810-812. https://doi.org/10.3171/jns.2004.100.5.0810
Taylor CL, Dutton K, Rappard G, Pride GL, Replogle R, Purdy PD et al. Complications of preoperative embolization of cerebral arteriovenous malformations. Journal of Neurosurgery. 2004 Jan 1;100(5):810-812. https://doi.org/10.3171/jns.2004.100.5.0810
Taylor, Christopher L. ; Dutton, Kim ; Rappard, George ; Pride, G. Lee ; Replogle, Robert ; Purdy, Phillip D. ; White, Jonathan ; Giller, Cole A. ; Kopitnik, Thomas A. ; Samson, Duke S. / Complications of preoperative embolization of cerebral arteriovenous malformations. In: Journal of Neurosurgery. 2004 ; Vol. 100, No. 5. pp. 810-812.
@article{299cfe5998db4b3f9fe8fa8157a17eae,
title = "Complications of preoperative embolization of cerebral arteriovenous malformations",
abstract = "Object. Preoperative embolization is viewed by the authors as a useful adjunct in the surgical management of cerebral arteriovenous malformations (AVMs). This study was performed to determine the rate of significant complication in patients undergoing this procedure. Methods. Demographic, anatomical, and procedure data were collected prospectively. The treating physician reported complications. In addition, a review of medical records including procedure reports, operative reports, and discharge summaries was performed. Univariate statistical analysis was performed to determine if any of the variables was predictive of a poor outcome of embolization (death or permanent neurological deficit). Endovascular procedures for embolization were performed 339 times in 201 patients during an 11-year period. Female patients comprised 53.7{\%} of the study group and 85.6{\%} of the AVMs were supratentorial. Embolization was performed using polyvinyl alcohol particles, N-butyl cyanoacrylate, detachable coils, and/or the liquid polymer Onyx. Analyzed by procedure, a poor result of embolization occurred in 7.7{\%}. Analyzed by patient, 11{\%} died or had a permanent neurological deficit as a result of the embolization. None of the demographic, anatomical, or procedure variables identified were predictive of a poor outcome. Conclusions. Preoperative embolization may gradually reduce flow to an AVM, reduce intraoperative blood loss, and reduce operative time. The risks of this procedure, however, are not insignificant and must be considered in planning treatment for patients with AVMs.",
keywords = "Arteriovenous malformation, Brain, Embolization, Endovascular therapy, Outcome analysis",
author = "Taylor, {Christopher L.} and Kim Dutton and George Rappard and Pride, {G. Lee} and Robert Replogle and Purdy, {Phillip D.} and Jonathan White and Giller, {Cole A.} and Kopitnik, {Thomas A.} and Samson, {Duke S.}",
year = "2004",
month = "1",
day = "1",
doi = "10.3171/jns.2004.100.5.0810",
language = "English (US)",
volume = "100",
pages = "810--812",
journal = "Journal of Neurosurgery",
issn = "0022-3085",
publisher = "American Association of Neurological Surgeons",
number = "5",

}

TY - JOUR

T1 - Complications of preoperative embolization of cerebral arteriovenous malformations

AU - Taylor, Christopher L.

AU - Dutton, Kim

AU - Rappard, George

AU - Pride, G. Lee

AU - Replogle, Robert

AU - Purdy, Phillip D.

AU - White, Jonathan

AU - Giller, Cole A.

AU - Kopitnik, Thomas A.

AU - Samson, Duke S.

PY - 2004/1/1

Y1 - 2004/1/1

N2 - Object. Preoperative embolization is viewed by the authors as a useful adjunct in the surgical management of cerebral arteriovenous malformations (AVMs). This study was performed to determine the rate of significant complication in patients undergoing this procedure. Methods. Demographic, anatomical, and procedure data were collected prospectively. The treating physician reported complications. In addition, a review of medical records including procedure reports, operative reports, and discharge summaries was performed. Univariate statistical analysis was performed to determine if any of the variables was predictive of a poor outcome of embolization (death or permanent neurological deficit). Endovascular procedures for embolization were performed 339 times in 201 patients during an 11-year period. Female patients comprised 53.7% of the study group and 85.6% of the AVMs were supratentorial. Embolization was performed using polyvinyl alcohol particles, N-butyl cyanoacrylate, detachable coils, and/or the liquid polymer Onyx. Analyzed by procedure, a poor result of embolization occurred in 7.7%. Analyzed by patient, 11% died or had a permanent neurological deficit as a result of the embolization. None of the demographic, anatomical, or procedure variables identified were predictive of a poor outcome. Conclusions. Preoperative embolization may gradually reduce flow to an AVM, reduce intraoperative blood loss, and reduce operative time. The risks of this procedure, however, are not insignificant and must be considered in planning treatment for patients with AVMs.

AB - Object. Preoperative embolization is viewed by the authors as a useful adjunct in the surgical management of cerebral arteriovenous malformations (AVMs). This study was performed to determine the rate of significant complication in patients undergoing this procedure. Methods. Demographic, anatomical, and procedure data were collected prospectively. The treating physician reported complications. In addition, a review of medical records including procedure reports, operative reports, and discharge summaries was performed. Univariate statistical analysis was performed to determine if any of the variables was predictive of a poor outcome of embolization (death or permanent neurological deficit). Endovascular procedures for embolization were performed 339 times in 201 patients during an 11-year period. Female patients comprised 53.7% of the study group and 85.6% of the AVMs were supratentorial. Embolization was performed using polyvinyl alcohol particles, N-butyl cyanoacrylate, detachable coils, and/or the liquid polymer Onyx. Analyzed by procedure, a poor result of embolization occurred in 7.7%. Analyzed by patient, 11% died or had a permanent neurological deficit as a result of the embolization. None of the demographic, anatomical, or procedure variables identified were predictive of a poor outcome. Conclusions. Preoperative embolization may gradually reduce flow to an AVM, reduce intraoperative blood loss, and reduce operative time. The risks of this procedure, however, are not insignificant and must be considered in planning treatment for patients with AVMs.

KW - Arteriovenous malformation

KW - Brain

KW - Embolization

KW - Endovascular therapy

KW - Outcome analysis

UR - http://www.scopus.com/inward/record.url?scp=11144355854&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=11144355854&partnerID=8YFLogxK

U2 - 10.3171/jns.2004.100.5.0810

DO - 10.3171/jns.2004.100.5.0810

M3 - Review article

VL - 100

SP - 810

EP - 812

JO - Journal of Neurosurgery

JF - Journal of Neurosurgery

SN - 0022-3085

IS - 5

ER -