Contemporary Perioperative Results of Isolated Aortic Valve Replacement for Aortic Stenosis

S. Chris Malaisrie, Patrick M. McCarthy, Edwin C. McGee, Richard Lee, Vera H. Rigolin, Charles J. Davidson, Nirat Beohar, Brittany Lapin, Haris Subačius, Robert O. Bonow

Research output: Contribution to journalArticle

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Abstract

Background: Transcatheter aortic valve implantation may become a potential treatment for high-risk patients with aortic stenosis (AS). We analyzed our contemporary series of isolated aortic valve replacement (AVR) for AS to determine implications for patients referred for AVR. Methods: From April 2004 through December 2008, 190 patients (mean age, 68 years; 68% men) underwent isolated AVR for AS. Mean ejection fraction was 0.58. Sixty-one percent underwent minimally invasive AVR and 18% were reoperations. Twenty-one percent were aged 80 years or older, and 34% were in New York Heart Association functional class III-IV. Estimated operative mortality was 3.6%. Results: Thirty-day mortality was 0%. One in-hospital death (0.5%) occurred from complications of an esophageal perforation. Reoperation for bleeding occurred in 4.7%. Acute renal failure developed in 2.1%. Actuarial survival was 97% at 1 year and 94% at 3 years. Hospital length of stay was 7.0 days for patients aged 80 and older vs 5.0 days (p < 0.001), and they were less likely to be discharged to home (50% vs 83%, p < 0.001). Conclusions: Contemporary results show that AVR for AS can be performed with low operative mortality and morbidity, although patients aged 80 years and older are at increased risk of prolonged recovery. Transcatheter aortic valve implantation may be an alternative for high-risk patients, but AVR is still appropriate for low-risk patients. The low risk of AVR supports the argument that asymptomatic patients who have a high likelihood of progression of AS may be considered for earlier surgical referral.

Original languageEnglish (US)
Pages (from-to)751-756
Number of pages6
JournalAnnals of Thoracic Surgery
Volume89
Issue number3
DOIs
StatePublished - Mar 1 2010

Fingerprint

Aortic Valve Stenosis
Aortic Valve
Reoperation
Mortality
Length of Stay
Esophageal Perforation
Acute Kidney Injury
Referral and Consultation
Hemorrhage
Morbidity
Survival

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

Cite this

Malaisrie, S. C., McCarthy, P. M., McGee, E. C., Lee, R., Rigolin, V. H., Davidson, C. J., ... Bonow, R. O. (2010). Contemporary Perioperative Results of Isolated Aortic Valve Replacement for Aortic Stenosis. Annals of Thoracic Surgery, 89(3), 751-756. https://doi.org/10.1016/j.athoracsur.2009.11.024

Contemporary Perioperative Results of Isolated Aortic Valve Replacement for Aortic Stenosis. / Malaisrie, S. Chris; McCarthy, Patrick M.; McGee, Edwin C.; Lee, Richard; Rigolin, Vera H.; Davidson, Charles J.; Beohar, Nirat; Lapin, Brittany; Subačius, Haris; Bonow, Robert O.

In: Annals of Thoracic Surgery, Vol. 89, No. 3, 01.03.2010, p. 751-756.

Research output: Contribution to journalArticle

Malaisrie, SC, McCarthy, PM, McGee, EC, Lee, R, Rigolin, VH, Davidson, CJ, Beohar, N, Lapin, B, Subačius, H & Bonow, RO 2010, 'Contemporary Perioperative Results of Isolated Aortic Valve Replacement for Aortic Stenosis', Annals of Thoracic Surgery, vol. 89, no. 3, pp. 751-756. https://doi.org/10.1016/j.athoracsur.2009.11.024
Malaisrie, S. Chris ; McCarthy, Patrick M. ; McGee, Edwin C. ; Lee, Richard ; Rigolin, Vera H. ; Davidson, Charles J. ; Beohar, Nirat ; Lapin, Brittany ; Subačius, Haris ; Bonow, Robert O. / Contemporary Perioperative Results of Isolated Aortic Valve Replacement for Aortic Stenosis. In: Annals of Thoracic Surgery. 2010 ; Vol. 89, No. 3. pp. 751-756.
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AU - Rigolin, Vera H.

AU - Davidson, Charles J.

AU - Beohar, Nirat

AU - Lapin, Brittany

AU - Subačius, Haris

AU - Bonow, Robert O.

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