Cytokeratin-positive, CD45-negative primary centroblastic lymphoma of the adrenal gland

A potential for a diagnostic pitfall

L. R. Donner, Frank Edmund Mott, I. Tafur

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

We report a case of cytokeratin-positive, CD45-negative primary polymorphic centroblastic lymphoma of the adrenal gland. Additional immunostaining, which demonstrated positivity for CD20 and κ light chain, as well as detection of the monoclonal rearrangement of the immunoglobulin heavy chain gene, helped to establish the diagnosis of lymphoma and to rule out an initially favored diagnosis of poorly differentiated carcinoma.

Original languageEnglish (US)
Pages (from-to)1104-1106
Number of pages3
JournalArchives of Pathology and Laboratory Medicine
Volume125
Issue number8
StatePublished - Aug 22 2001

Fingerprint

Adrenal Glands
Keratins
Lymphoma
Immunoglobulin Heavy Chain Genes
Carcinoma
Light

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology

Cite this

Cytokeratin-positive, CD45-negative primary centroblastic lymphoma of the adrenal gland : A potential for a diagnostic pitfall. / Donner, L. R.; Mott, Frank Edmund; Tafur, I.

In: Archives of Pathology and Laboratory Medicine, Vol. 125, No. 8, 22.08.2001, p. 1104-1106.

Research output: Contribution to journalArticle

@article{2faebe8a52ca4b41ad9add773b2813b9,
title = "Cytokeratin-positive, CD45-negative primary centroblastic lymphoma of the adrenal gland: A potential for a diagnostic pitfall",
abstract = "We report a case of cytokeratin-positive, CD45-negative primary polymorphic centroblastic lymphoma of the adrenal gland. Additional immunostaining, which demonstrated positivity for CD20 and κ light chain, as well as detection of the monoclonal rearrangement of the immunoglobulin heavy chain gene, helped to establish the diagnosis of lymphoma and to rule out an initially favored diagnosis of poorly differentiated carcinoma.",
author = "Donner, {L. R.} and Mott, {Frank Edmund} and I. Tafur",
year = "2001",
month = "8",
day = "22",
language = "English (US)",
volume = "125",
pages = "1104--1106",
journal = "Archives of Pathology and Laboratory Medicine",
issn = "0003-9985",
publisher = "College of American Pathologists",
number = "8",

}

TY - JOUR

T1 - Cytokeratin-positive, CD45-negative primary centroblastic lymphoma of the adrenal gland

T2 - A potential for a diagnostic pitfall

AU - Donner, L. R.

AU - Mott, Frank Edmund

AU - Tafur, I.

PY - 2001/8/22

Y1 - 2001/8/22

N2 - We report a case of cytokeratin-positive, CD45-negative primary polymorphic centroblastic lymphoma of the adrenal gland. Additional immunostaining, which demonstrated positivity for CD20 and κ light chain, as well as detection of the monoclonal rearrangement of the immunoglobulin heavy chain gene, helped to establish the diagnosis of lymphoma and to rule out an initially favored diagnosis of poorly differentiated carcinoma.

AB - We report a case of cytokeratin-positive, CD45-negative primary polymorphic centroblastic lymphoma of the adrenal gland. Additional immunostaining, which demonstrated positivity for CD20 and κ light chain, as well as detection of the monoclonal rearrangement of the immunoglobulin heavy chain gene, helped to establish the diagnosis of lymphoma and to rule out an initially favored diagnosis of poorly differentiated carcinoma.

UR - http://www.scopus.com/inward/record.url?scp=0034899547&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034899547&partnerID=8YFLogxK

M3 - Article

VL - 125

SP - 1104

EP - 1106

JO - Archives of Pathology and Laboratory Medicine

JF - Archives of Pathology and Laboratory Medicine

SN - 0003-9985

IS - 8

ER -