Cytoplasmic and nuclear inheritance of resistance to alkylguanidines and ethidium bromide in a petite-negative yeast

Aurora Brunner, J. Mas, Esteban Celis, J. R. Mattoon

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Mutants of the petite-negative yeast, Kluyveromyceslactis, resistant to the inhibitors of oxidative phosphorylation, decamethylenediguanidine and octylguanidine were isolated from medium containing ethidium bromide. All mutants were resistant to ethidium bromide; some mutants were resistant to both alkylguanidines, some to one, others to neither. Both nuclear and cytoplasmic inheritance of resistance to decamethylenediguanidine and ethidium bromide was demonstrated by tetrad analysis.

Original languageEnglish (US)
Pages (from-to)638-644
Number of pages7
JournalBiochemical and Biophysical Research Communications
Volume53
Issue number2
DOIs
StatePublished - Jul 17 1973
Externally publishedYes

Fingerprint

Extrachromosomal Inheritance
Ethidium
Yeast
Yeasts
Oxidative Phosphorylation

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

Cite this

Cytoplasmic and nuclear inheritance of resistance to alkylguanidines and ethidium bromide in a petite-negative yeast. / Brunner, Aurora; Mas, J.; Celis, Esteban; Mattoon, J. R.

In: Biochemical and Biophysical Research Communications, Vol. 53, No. 2, 17.07.1973, p. 638-644.

Research output: Contribution to journalArticle

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