Defining hirsutism in Chinese women: A cross-sectional study

Xiaomiao Zhao, Renmin Ni, Lin Li, Yaqin Mo, Jia Huang, Meifeng Huang, Ricardo Azziz, Dongzi Yang

Research output: Contribution to journalArticle

58 Scopus citations

Abstract

Objective: To determine the normative cut-off score that defines hirsutism among Chinese women, and the effect of age, menstrual irregularities, and polycystic ovaries on the same. Design: Cross-sectional, population-based study. Setting: A multistage systematic cluster random sampling among 16 communities from two rural and two city regions. Patient(s): A representative sample of 2,988 women aged 20-45 years from the general population of Southern China. Intervention(s): Subjects underwent physical and ultrasound evaluations. Main Outcome Measure(s): Terminal hair growth was assessed using the modified Ferriman-Gallwey (mFG) scoring system. Result(s): An mFG score ≥5 was observed in 10% and a score of ≥2 in 25% of the subjects. Cluster analysis identified an mFG score of 5 as the cut-off value that defines abnormal terminal facial and body hair growth in a male pattern (i.e., hirsutism) in the total population; scores of 6, 5, and 4 for women aged 20-25, 26-30, and >30 years, respectively. Defined by these cut-off values, the prevalence of hirsutism in our total population was 10.5%; and decreased with increasing age: 14.4%, 10.7%, 7.9%, 3.6%, and 1.5%, respectively, in women aged 20-25, 26-30, 31-35, 36-40, and 41-45 years. Furthermore, the incidence of acne, menses irregularities, polycystic ovaries, and acanthosis nigricans were significantly increased among the hirsute women. Conclusion(s): An mFG score of 5 or greater indicates hair growth above the norm among women in the general Southern Chinese population, a cut-off value that decreases with increasing age.

Original languageEnglish (US)
Pages (from-to)792-796
Number of pages5
JournalFertility and sterility
Volume96
Issue number3
DOIs
StatePublished - Sep 1 2011

Keywords

  • Hirsutism
  • modified Ferriman-Gallwey score
  • normal cut-off value
  • polycystic ovary syndrome

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

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  • Cite this

    Zhao, X., Ni, R., Li, L., Mo, Y., Huang, J., Huang, M., Azziz, R., & Yang, D. (2011). Defining hirsutism in Chinese women: A cross-sectional study. Fertility and sterility, 96(3), 792-796. https://doi.org/10.1016/j.fertnstert.2011.06.040