Delayed Arterial Switch Operation for D-Transposition of the Great Arteries and Glucocorticoid Remediable Aldosteronism

Nofil Arain, Elizabeth Braunlin, James St Louis, Roosevelt Bryant

Research output: Contribution to journalReview articlepeer-review

Abstract

The Jatene arterial switch operation (ASO) for dextro-transposition of the great arteries is ideally performed within the first 2 weeks of life. Clinical circumstances, however, may dictate a delayed ASO and left ventricle “retraining” prior to the procedure. Glucocorticoid remediable aldosteronism (GRA) accounts for 0.5% to 1% of primary aldosteronism. It presents as severe hypertension in infants and children, with poor response to standard antihypertensive medications. To the authors’ knowledge, this is the first reported case of GRA in the context of transposition physiology. The management of GRA and a rationale for delayed ASO are discussed.

Original languageEnglish (US)
Pages (from-to)316-317
Number of pages2
JournalWorld Journal for Pediatric and Congenital Heart Surgery
Volume2
Issue number2
DOIs
StatePublished - Apr 2011
Externally publishedYes

Keywords

  • arterial switch operation
  • comorbidity
  • congenital heart surgery
  • endocrinology
  • preconditioning

ASJC Scopus subject areas

  • Surgery
  • Pediatrics, Perinatology, and Child Health
  • Cardiology and Cardiovascular Medicine

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