Diabetes insipidus: An unusual presentation of adenocarcinoma of the lung in a patient with no identifiable lung mass

Shuchi Gulati, Christoper Kiefer, Nagla Abdel Karim

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Context: Lung cancers are known to metastasize to unusual sites. Despite this knowledge often times the diagnosis of a primary lung cancer gets delayed especially when the patient presents without respiratory symptoms. Case Report: The patient discussed in our review is a 47-year-old female, smoker who had presented to several hospitals with months of headache, nausea and intermittent episodes of vomiting. She was noted to have hypernatremia due to diabetes insipidus and a pituitary lesion on her magnetic resonance images. The pituitary mass on biopsy was found to represent a metastatic focus from a primary lung adenocarcinoma. Conclusion: Clinicians should be aware of malignancies that are well known to metastasize to the posterior pituitary. Conversely, since not every patient presents with symptoms of metastasis, there is a need to recognize the clinical syndromes (e. g., diabetes insipidus-like symptoms or more subtle symptoms like cranial nerve palsies) associated with potential metastasis to the pituitary.

Original languageEnglish (US)
Pages (from-to)476-479
Number of pages4
JournalNorth American Journal of Medical Sciences
Volume7
Issue number10
DOIs
StatePublished - Oct 30 2015
Externally publishedYes

Keywords

  • Adenocarcinoma
  • Adults
  • Diabetes insipidus
  • Humans
  • Pituitary neoplasms

ASJC Scopus subject areas

  • Medicine(all)

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