Diabetes insipidus: An unusual presentation of adenocarcinoma of the lung in a patient with no identifiable lung mass

Shuchi Gulati, Christoper Kiefer, Nagla Abdel Karim

Research output: Contribution to journalArticle

Abstract

Context: Lung cancers are known to metastasize to unusual sites. Despite this knowledge often times the diagnosis of a primary lung cancer gets delayed especially when the patient presents without respiratory symptoms. Case Report: The patient discussed in our review is a 47-year-old female, smoker who had presented to several hospitals with months of headache, nausea and intermittent episodes of vomiting. She was noted to have hypernatremia due to diabetes insipidus and a pituitary lesion on her magnetic resonance images. The pituitary mass on biopsy was found to represent a metastatic focus from a primary lung adenocarcinoma. Conclusion: Clinicians should be aware of malignancies that are well known to metastasize to the posterior pituitary. Conversely, since not every patient presents with symptoms of metastasis, there is a need to recognize the clinical syndromes (e. g., diabetes insipidus-like symptoms or more subtle symptoms like cranial nerve palsies) associated with potential metastasis to the pituitary.

Original languageEnglish (US)
Pages (from-to)476-479
Number of pages4
JournalNorth American Journal of Medical Sciences
Volume7
Issue number10
DOIs
StatePublished - Oct 30 2015
Externally publishedYes

Fingerprint

Diabetes Insipidus
Lung
Lung Neoplasms
Neurogenic Diabetes Insipidus
Neoplasm Metastasis
Hypernatremia
Cranial Nerve Diseases
Nausea
Vomiting
Headache
Magnetic Resonance Spectroscopy
Biopsy
Adenocarcinoma of lung
Neoplasms

Keywords

  • Adenocarcinoma
  • Adults
  • Diabetes insipidus
  • Humans
  • Pituitary neoplasms

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Diabetes insipidus : An unusual presentation of adenocarcinoma of the lung in a patient with no identifiable lung mass. / Gulati, Shuchi; Kiefer, Christoper; Karim, Nagla Abdel.

In: North American Journal of Medical Sciences, Vol. 7, No. 10, 30.10.2015, p. 476-479.

Research output: Contribution to journalArticle

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