Disseminated Histoplasmosis Presenting as Weight Loss and Hypercalcemia in a Renal Transplant Patient With Prior History of Subtotal Parathyroidectomy: Histoplasmosis Presenting as Weight Loss and Hypercalcemia

Imran Gani, Amanda Barrett, Laura L Mulloy, Rajan Kapoor

Research output: Contribution to journalReview articlepeer-review

Abstract

Hypercalcemia and weight loss in a renal transplant patient especially with history of parathyroidectomy raises concern for an underlying malignancy, fungal infections or granulomatous disease. We present a case of 45-year-old male with history of subtotal parathyroidectomy presented with severe persistent hypercalcemia, acute kidney injury (AKI) and significant weight loss. An extensive workup revealed disseminated histoplasmosis. Hypercalcemia (which was refractory to initial medical management) and other symptoms resolved after a few weeks of initiating the antifungal treatment.

Original languageEnglish (US)
JournalAmerican Journal of the Medical Sciences
DOIs
StateAccepted/In press - 2020

Keywords

  • Acute kidney injury
  • Histoplasmosis
  • Hypercalcemia
  • Renal transplant
  • Weight loss

ASJC Scopus subject areas

  • Medicine(all)

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