Distribution of 14C-formaldehyde after pulpotomy with formocresol.

D. R. Myers, H. K. Shoaf, T. R. Dirksen, David Henry Pashley, Gary M. Whitford, K. E. Reynolds

Research output: Contribution to journalArticle

88 Citations (Scopus)

Abstract

Pulpotomies were performed on rhesus monkeys with use of formocresol to determine if there was uptake of 14C-formaldehyde into the systemic circulation after formocresol pulpotomies. Five-minute exposure of pulpal tissue to the 14C-formocresol resulted in the systemic absorption of approximately 1% of the dose. Two hours of exposure of pulp tissue to the 14C-formocresol did not increase the systemic absorption. Multiple sequential pulpotomies resulted in proportionately higher systemic absorption of 14C-formaldehyde. Application of 131I to pulpotomy sites indicated that formocresol compromises the microcirculation of the dental pulp. Autoradiography disclosed extensive concentrations of 14C-formaldehyde in the pulp, dentin, periodontal ligament, and bone.

Original languageEnglish (US)
Pages (from-to)805-813
Number of pages9
JournalJournal of the American Dental Association (1939)
Volume96
Issue number5
DOIs
StatePublished - Jan 1 1978

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Pulpotomy
Formaldehyde
Dental Pulp
Periodontal Ligament
Dentin
Microcirculation
Macaca mulatta
Autoradiography
formocresol
Bone and Bones
Physiological Absorption

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Distribution of 14C-formaldehyde after pulpotomy with formocresol. / Myers, D. R.; Shoaf, H. K.; Dirksen, T. R.; Pashley, David Henry; Whitford, Gary M.; Reynolds, K. E.

In: Journal of the American Dental Association (1939), Vol. 96, No. 5, 01.01.1978, p. 805-813.

Research output: Contribution to journalArticle

Myers, D. R. ; Shoaf, H. K. ; Dirksen, T. R. ; Pashley, David Henry ; Whitford, Gary M. ; Reynolds, K. E. / Distribution of 14C-formaldehyde after pulpotomy with formocresol. In: Journal of the American Dental Association (1939). 1978 ; Vol. 96, No. 5. pp. 805-813.
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