Abstract
Pulpotomies were performed on rhesus monkeys with use of formocresol to determine if there was uptake of 14C-formaldehyde into the systemic circulation after formocresol pulpotomies. Five-minute exposure of pulpal tissue to the 14C-formocresol resulted in the systemic absorption of approximately 1% of the dose. Two hours of exposure of pulp tissue to the 14C-formocresol did not increase the systemic absorption. Multiple sequential pulpotomies resulted in proportionately higher systemic absorption of 14C-formaldehyde. Application of 131I to pulpotomy sites indicated that formocresol compromises the microcirculation of the dental pulp. Autoradiography disclosed extensive concentrations of 14C-formaldehyde in the pulp, dentin, periodontal ligament, and bone.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 805-813 |
| Number of pages | 9 |
| Journal | Journal of the American Dental Association (1939) |
| Volume | 96 |
| Issue number | 5 |
| DOIs | |
| State | Published - Jan 1 1978 |
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ASJC Scopus subject areas
- Dentistry(all)
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Distribution of 14C-formaldehyde after pulpotomy with formocresol. / Myers, D. R.; Shoaf, H. K.; Dirksen, T. R.; Pashley, David Henry; Whitford, Gary M.; Reynolds, K. E.
In: Journal of the American Dental Association (1939), Vol. 96, No. 5, 01.01.1978, p. 805-813.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Distribution of 14C-formaldehyde after pulpotomy with formocresol.
AU - Myers, D. R.
AU - Shoaf, H. K.
AU - Dirksen, T. R.
AU - Pashley, David Henry
AU - Whitford, Gary M.
AU - Reynolds, K. E.
PY - 1978/1/1
Y1 - 1978/1/1
N2 - Pulpotomies were performed on rhesus monkeys with use of formocresol to determine if there was uptake of 14C-formaldehyde into the systemic circulation after formocresol pulpotomies. Five-minute exposure of pulpal tissue to the 14C-formocresol resulted in the systemic absorption of approximately 1% of the dose. Two hours of exposure of pulp tissue to the 14C-formocresol did not increase the systemic absorption. Multiple sequential pulpotomies resulted in proportionately higher systemic absorption of 14C-formaldehyde. Application of 131I to pulpotomy sites indicated that formocresol compromises the microcirculation of the dental pulp. Autoradiography disclosed extensive concentrations of 14C-formaldehyde in the pulp, dentin, periodontal ligament, and bone.
AB - Pulpotomies were performed on rhesus monkeys with use of formocresol to determine if there was uptake of 14C-formaldehyde into the systemic circulation after formocresol pulpotomies. Five-minute exposure of pulpal tissue to the 14C-formocresol resulted in the systemic absorption of approximately 1% of the dose. Two hours of exposure of pulp tissue to the 14C-formocresol did not increase the systemic absorption. Multiple sequential pulpotomies resulted in proportionately higher systemic absorption of 14C-formaldehyde. Application of 131I to pulpotomy sites indicated that formocresol compromises the microcirculation of the dental pulp. Autoradiography disclosed extensive concentrations of 14C-formaldehyde in the pulp, dentin, periodontal ligament, and bone.
UR - http://www.scopus.com/inward/record.url?scp=0017970554&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0017970554&partnerID=8YFLogxK
U2 - 10.14219/jada.archive.1978.0187
DO - 10.14219/jada.archive.1978.0187
M3 - Article
C2 - 418090
AN - SCOPUS:0017970554
VL - 96
SP - 805
EP - 813
JO - Journal of the American Dental Association
JF - Journal of the American Dental Association
SN - 0002-8177
IS - 5
ER -