Do bone marrow cells generate neurons?

David C Hess, William D Hill, James Edwin Carroll, Cesar V. Borlongan

Research output: Contribution to journalReview article

28 Citations (Scopus)

Abstract

In the past 5 years, accumulating evidence has demonstrated plasticity of bone marrow-derived cells. Bone marrow-derived cells display the capacity to change their fate, differentiating into hepatocytes, endothelial cells, muscle cells, and cardiomyocytes, and even neurons. The findings that bone marrow cells differentiate into neurons in vitro and in vivo challenge previous assumptions that tissue-specific stem cells give rise only to cells of their organ of origin and do not cross lineages.

Original languageEnglish (US)
Pages (from-to)483-485
Number of pages3
JournalArchives of Neurology
Volume61
Issue number4
DOIs
StatePublished - Apr 1 2004

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Bone Marrow Cells
Neurons
Cardiac Myocytes
Muscle Cells
Hepatocytes
Stem Cells
Endothelial Cells
Neuron
Bone Marrow
Cells
In Vitro Techniques

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Do bone marrow cells generate neurons? / Hess, David C; Hill, William D; Carroll, James Edwin; Borlongan, Cesar V.

In: Archives of Neurology, Vol. 61, No. 4, 01.04.2004, p. 483-485.

Research output: Contribution to journalReview article

Hess, David C ; Hill, William D ; Carroll, James Edwin ; Borlongan, Cesar V. / Do bone marrow cells generate neurons?. In: Archives of Neurology. 2004 ; Vol. 61, No. 4. pp. 483-485.
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