Do bone marrow cells generate neurons?

David C. Hess, William D. Hill, James E. Carroll, Cesar V. Borlongan

Research output: Contribution to journalReview article

28 Scopus citations


In the past 5 years, accumulating evidence has demonstrated plasticity of bone marrow-derived cells. Bone marrow-derived cells display the capacity to change their fate, differentiating into hepatocytes, endothelial cells, muscle cells, and cardiomyocytes, and even neurons. The findings that bone marrow cells differentiate into neurons in vitro and in vivo challenge previous assumptions that tissue-specific stem cells give rise only to cells of their organ of origin and do not cross lineages.

Original languageEnglish (US)
Pages (from-to)483-485
Number of pages3
JournalArchives of Neurology
Issue number4
Publication statusPublished - Apr 1 2004


ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology

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