Effect of charge on the distribution and retention of macromolecules in the artery wall

Ann L. Baldwin, Lisa M. Wilson, Brooke J. McGuire

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Experiments were performed on rabbit aorta and femoral arteries to test the hypothesis that neutral dextran, of a similar molecular weight to albumin, does not show preferential lamellar binding and is rapidly removed from the arterial wall by immersion in tracer-free solution. Results demonstrate that the distribution of macromolecules within the aortic wall is not just size dependent, but also depend on the degree of interaction between the macromolecule and arterial wall components, such as elastin.

Original languageEnglish (US)
Title of host publicationAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED
PublisherASME
Pages475-476
Number of pages2
Volume42
ISBN (Print)0791816117
Publication statusPublished - Dec 1 1999
Externally publishedYes
Event1999 Bioengineering Conference - Big Sky, MT, USA
Duration: Jun 16 1999Jun 20 1999

Other

Other1999 Bioengineering Conference
CityBig Sky, MT, USA
Period6/16/996/20/99

    Fingerprint

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Baldwin, A. L., Wilson, L. M., & McGuire, B. J. (1999). Effect of charge on the distribution and retention of macromolecules in the artery wall. In American Society of Mechanical Engineers, Bioengineering Division (Publication) BED (Vol. 42, pp. 475-476). ASME.