Effect of oral estrogen on substrate utilization in postmenopausal women

Rebecca Lwin, Betty Darnell, Robert Oster, Jeannine Lawrence, Jill Foster, Ricardo Azziz, Barbara A. Gower

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

We tested the hypothesis that a 2-month intervention with unopposed oral conjugated equine estrogens (0.625 mg/d) would decrease lipid oxidation, as assessed by 24-hour, whole-room, indirect calorimetry in 14 postmenopausal women. Estrogen (E) treatment was associated with declines in both 24-hour and postprandial lipid oxidation and an increase in fat mass (mean [±SD] 2-month difference 1.1 ± 1.0 kg; mean 6-month difference 1.8 ± 2.2 kg), suggesting that, on an acute basis, oral E may increase adiposity by limiting lipid oxidation.

Original languageEnglish (US)
Pages (from-to)1275-1278
Number of pages4
JournalFertility and Sterility
Volume90
Issue number4
DOIs
StatePublished - Oct 1 2008

Fingerprint

Estrogens
Lipids
Conjugated (USP) Estrogens
Indirect Calorimetry
Adiposity
Fats
Therapeutics

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Reproductive Medicine

Cite this

Lwin, R., Darnell, B., Oster, R., Lawrence, J., Foster, J., Azziz, R., & Gower, B. A. (2008). Effect of oral estrogen on substrate utilization in postmenopausal women. Fertility and Sterility, 90(4), 1275-1278. https://doi.org/10.1016/j.fertnstert.2007.07.1317

Effect of oral estrogen on substrate utilization in postmenopausal women. / Lwin, Rebecca; Darnell, Betty; Oster, Robert; Lawrence, Jeannine; Foster, Jill; Azziz, Ricardo; Gower, Barbara A.

In: Fertility and Sterility, Vol. 90, No. 4, 01.10.2008, p. 1275-1278.

Research output: Contribution to journalArticle

Lwin, R, Darnell, B, Oster, R, Lawrence, J, Foster, J, Azziz, R & Gower, BA 2008, 'Effect of oral estrogen on substrate utilization in postmenopausal women', Fertility and Sterility, vol. 90, no. 4, pp. 1275-1278. https://doi.org/10.1016/j.fertnstert.2007.07.1317
Lwin R, Darnell B, Oster R, Lawrence J, Foster J, Azziz R et al. Effect of oral estrogen on substrate utilization in postmenopausal women. Fertility and Sterility. 2008 Oct 1;90(4):1275-1278. https://doi.org/10.1016/j.fertnstert.2007.07.1317
Lwin, Rebecca ; Darnell, Betty ; Oster, Robert ; Lawrence, Jeannine ; Foster, Jill ; Azziz, Ricardo ; Gower, Barbara A. / Effect of oral estrogen on substrate utilization in postmenopausal women. In: Fertility and Sterility. 2008 ; Vol. 90, No. 4. pp. 1275-1278.
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