Effect of prosthetic mitral valve geometry and orientation on flow dynamics in a model human left ventricle

K. B. Chandran, R. Schoephoerster, Kevin C Dellsperger

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Pulsatile flow dynamics through bileaflet (St Jude and Duromedics), tilting disc (Bjork-Shiley and Omniscience), caged ball (Starr-Edwards), pericardial (Edwards) and porcine (Carpentier-Edwards) mitral valves in a model human left ventricle (LV) were studied. The model human ventricle, obtained from an in situ diastolic casting, was incorporated into a mock circulatory system. Measurements were made at various heart rates and flow rates. These included the transvalvular pressure drop and regurgitation in percent and cm3 beat-1. The effect of valve geometry and the orientation of the valve with respect to the valve annulus was analyzed using a flow visualization technique. Qualitative flow visualization study indicates certain preferred orientations for the tilting disc and bileaflet valve prostheses in order to obtain a smooth washout of flow in the LV chamber.

Original languageEnglish (US)
JournalJournal of Biomechanics
Volume22
Issue number1
DOIs
StatePublished - Jan 1 1989

Fingerprint

Flow visualization
Prosthetics
Mitral Valve
Heart Ventricles
Pulsatile Flow
Pulsatile flow
Geometry
Cardiovascular System
Prostheses and Implants
Pressure drop
Casting
Swine
Heart Rate
Flow rate
Pressure

ASJC Scopus subject areas

  • Biophysics
  • Orthopedics and Sports Medicine
  • Biomedical Engineering
  • Rehabilitation

Cite this

Effect of prosthetic mitral valve geometry and orientation on flow dynamics in a model human left ventricle. / Chandran, K. B.; Schoephoerster, R.; Dellsperger, Kevin C.

In: Journal of Biomechanics, Vol. 22, No. 1, 01.01.1989.

Research output: Contribution to journalArticle

Chandran, K. B. ; Schoephoerster, R. ; Dellsperger, Kevin C. / Effect of prosthetic mitral valve geometry and orientation on flow dynamics in a model human left ventricle. In: Journal of Biomechanics. 1989 ; Vol. 22, No. 1.
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