Epigenetics in polycystic ovary syndrome

a pilot study of global DNA methylation

Ning Xu, Ricardo Azziz, Mark O. Goodarzi

Research output: Contribution to journalArticle

57 Citations (Scopus)

Abstract

The percent global methylation of peripheral blood DNA was not significantly altered in 20 women with polycystic ovary syndrome (PCOS) compared with 20 controls. The study of specific tissues and target genomic regions will be required to further determine whether epigenetic alteration influences the development of PCOS.

Original languageEnglish (US)
JournalFertility and sterility
Volume94
Issue number2
DOIs
StatePublished - Jan 1 2010

Fingerprint

Polycystic Ovary Syndrome
DNA Methylation
Epigenomics
Methylation
DNA

Keywords

  • DNA methylation
  • Epigenetics
  • polycystic ovary syndrome

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

Cite this

Epigenetics in polycystic ovary syndrome : a pilot study of global DNA methylation. / Xu, Ning; Azziz, Ricardo; Goodarzi, Mark O.

In: Fertility and sterility, Vol. 94, No. 2, 01.01.2010.

Research output: Contribution to journalArticle

Xu, Ning ; Azziz, Ricardo ; Goodarzi, Mark O. / Epigenetics in polycystic ovary syndrome : a pilot study of global DNA methylation. In: Fertility and sterility. 2010 ; Vol. 94, No. 2.
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