Erythropoiesis inhibitory factor(s) from human plasma and urine: The production and application of a neutralizing anti-EIF serum

Frederick A. Garver, Willie A. Neal, Jasper P. Lewis, Hernan E. Grenett, Charles L. Lutcher, Takeshi Ozawa, Russell R. Moores, Claude Starr Wright

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

The erythropoiesis inhibitory fraction (EIF) isolated from different plasmas is equally effective on a weight basis. However, the yield of the plasma EIF fraction varies relative to the source. In general, the amounts of the inhibitor fraction seem to increase with, but not parallel to, increased erythropoiesis. A young girl with recessive erythrocytosis, and a renal transplant patient, however, have a relative deficiency of the EIF fraction which could explain the erythrocytosis.

Original languageEnglish (US)
Pages (from-to)174-185
Number of pages12
JournalBiochemical medicine
Volume25
Issue number2
DOIs
StatePublished - Apr 1981

ASJC Scopus subject areas

  • Biochemistry

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