Extra Gonadal Germ Cell Tumours

Report of Two Cases

Lalit Kumar, Sunesh Kumar, R. M. Kamble, Suash Sharma

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Extra gonadal germ cell tumours (EGGCT) in women are rare. We report here two such patients. The clinical and laboratory features were — young age, 25 and 22 years, midline location (mediastinum, scalp), elevated tumour marker and normal ovaries on CAT scan. The histological subtype was embryonal carcinoma in both cases. Complete response (CR) was achieved with cisplatin based chemotherapy (CT). Both patients had return of normal ovarian functions and have delivered normal babies (1st patient one, 2nd patient 2 babies). Both remain asymptomatic and disease‐free at 30 + and 55 + months follow‐up. We conclude that patients with EGGCT after treatment with cisplatin based CT achieve CR with return of normal ovarian functions and prolonged survival.

Original languageEnglish (US)
Pages (from-to)257-262
Number of pages6
JournalAsia‐Oceania Journal of Obstetrics and Gynaecology
Volume20
Issue number3
DOIs
StatePublished - Jan 1 1994
Externally publishedYes

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Germ Cell and Embryonal Neoplasms
Cisplatin
Embryonal Carcinoma
Drug Therapy
Mediastinum
Tumor Biomarkers
Scalp
Ovary
Survival

Keywords

  • cisplatin based chemotherapy
  • extra gonadal germ cell tumour
  • germ cell tumor

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Extra Gonadal Germ Cell Tumours : Report of Two Cases. / Kumar, Lalit; Kumar, Sunesh; Kamble, R. M.; Sharma, Suash.

In: Asia‐Oceania Journal of Obstetrics and Gynaecology, Vol. 20, No. 3, 01.01.1994, p. 257-262.

Research output: Contribution to journalArticle

Kumar, Lalit ; Kumar, Sunesh ; Kamble, R. M. ; Sharma, Suash. / Extra Gonadal Germ Cell Tumours : Report of Two Cases. In: Asia‐Oceania Journal of Obstetrics and Gynaecology. 1994 ; Vol. 20, No. 3. pp. 257-262.
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