Extracellular calcium and magnesium, intracellular cyclic AMP, and cell division in Tetrahymen a pyriformis

Mary L. Hilfiker, William Joseph Higgins

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

1. 1. T. pyriformis required ≥ 0.2 mM extracellular magnesium but not exogenous calcium for population growth and DNA synthesis. 2. 2. The intracellular cyclic AMP levels of T. pyriformis were inversely related to cell division rates. 3. 3. When cells were incubated in medium with no added magnesium, minimal cell division occurred, and the intracellular cyclic AMP concentrations were 5-fold greater (100 pmol/mg protein) than in cells in medium with 2 mM magnesium (20 pmol/mg protein). 4. 4. When 2 mM magnesium was added to the cells incubated initially in medium containing < 0.2 mM magnesium, the rate of cell division increased and intracellular cyclic AMP levels declined.

Original languageEnglish (US)
Pages (from-to)43-48
Number of pages6
JournalComparative Biochemistry and Physiology -- Part A: Physiology
Volume68
Issue number1
DOIs
StatePublished - Jan 1 1981

ASJC Scopus subject areas

  • Physiology

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