Fertility in men with Klinefleter syndrome.

Christopher P. Houk, Alan Rogol, Peter A. Lee

Research output: Contribution to journalReview article

11 Citations (Scopus)

Abstract

Klinefelter syndrome is an important cause of infertility among men. Although early development of the testes may appear normal, there is profound loss of germ cells during early-to-mid pubertal maturation. Spermatogenesis may be preserved in a small percent of tubules and these tubules may be available to artificial reproductive techniques for the retrieval and subsequent in vitro fertilization of extracted ova. Ethical and legal issues including risk-benefit consideration must be evaluated before implementing fertility preservation procedures in minors.

Original languageEnglish (US)
Pages (from-to)182-186
Number of pages5
JournalPediatric endocrinology reviews : PER
Volume8 Suppl 1
StatePublished - Dec 1 2010

Fingerprint

Fertility Preservation
Reproductive Techniques
Minors
Klinefelter Syndrome
Spermatogenesis
Fertilization in Vitro
Germ Cells
Ethics
Infertility
Ovum
Fertility
Testis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Endocrinology, Diabetes and Metabolism

Cite this

Fertility in men with Klinefleter syndrome. / Houk, Christopher P.; Rogol, Alan; Lee, Peter A.

In: Pediatric endocrinology reviews : PER, Vol. 8 Suppl 1, 01.12.2010, p. 182-186.

Research output: Contribution to journalReview article

Houk, CP, Rogol, A & Lee, PA 2010, 'Fertility in men with Klinefleter syndrome.', Pediatric endocrinology reviews : PER, vol. 8 Suppl 1, pp. 182-186.
Houk, Christopher P. ; Rogol, Alan ; Lee, Peter A. / Fertility in men with Klinefleter syndrome. In: Pediatric endocrinology reviews : PER. 2010 ; Vol. 8 Suppl 1. pp. 182-186.
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