The stem cell source of neural and glial progenitors in the periventricular regions of the adult forebrain has remained uncertain and controversial. Using a cell specific genetic approach we rule out Foxj1+ ependymal cells as stem cells participating in neurogenesis and gliogenesis in response to acute injury or stroke in the mouse forebrain. Non stem-And progenitor-like responses of Foxj1+ ependymal cells to injury and stroke remain to be defined and investigated.
|Original language||English (US)|
|State||Published - Dec 1 2018|
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