Fragile X in a Survey of 75 Autistic Males

M. S. Watson, J. F. Leckman, B. Annex, W. R. Breg, D. Boles, F. R. Volkmar, D. J. Cohen, C. Carter

Research output: Contribution to journalLetterpeer-review

53 Scopus citations


To the Editor: There are several reports of fragile X in male patients previously diagnosed as having infantile autism or mental retardation with “autistic features.”1 2 3 4 However, there have been no published reports on the prevalence of the fragile X syndrome in populations of autistic males. We have screened systematically for fragile X in 76 subjects with infantile autism as defined by Diagnostic and Statistical Manual criteria.5 Cell culture and harvest methods were the same as those previously described.6,7 Sixty cases were identified in special facilities for mentally retarded or autistic persons. At the Southbury Training School, a state institution with.

Original languageEnglish (US)
Pages (from-to)1462
Number of pages1
JournalNew England Journal of Medicine
Issue number22
StatePublished - May 31 1984
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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