Genetic testing for lung cancer risk: If physicians can do it, should they?

Theodore W. Marcy, Michael Edward Stefanek, Kimberly M. Thompson

Research output: Contribution to journalReview article

11 Citations (Scopus)

Abstract

Advances in genetics have increased our ability to assess an individual's genetic risk for disease. There is a hypothesis that genetic test results will motivate high-risk individuals to reduce harmful exposures, to increase their surveillance for disease, or to seek preventive treatments. However, genetic testing for genes associated with an increased risk of lung cancer would not change physicians' recommendations regarding smoking cessation. Limited studies suggest that test results that demonstrate an increased risk of lung cancer do not improve smoking cessation success. These test results may even distort an individual's risk perceptions. Before recommending genetic testing to assess risk for disease, physicians need to consider whether knowledge about genetic susceptibility will alter patient management.

Original languageEnglish (US)
Pages (from-to)946-951
Number of pages6
JournalJournal of General Internal Medicine
Volume17
Issue number12
DOIs
StatePublished - Jan 1 2002
Externally publishedYes

Fingerprint

Genetic Testing
Lung Neoplasms
Physicians
Smoking Cessation
Inborn Genetic Diseases
Aptitude
Genetic Predisposition to Disease
Genes

Keywords

  • Genetic counseling
  • Genetic screening
  • Lung neoplasms
  • Smoking

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Genetic testing for lung cancer risk : If physicians can do it, should they? / Marcy, Theodore W.; Stefanek, Michael Edward; Thompson, Kimberly M.

In: Journal of General Internal Medicine, Vol. 17, No. 12, 01.01.2002, p. 946-951.

Research output: Contribution to journalReview article

Marcy, Theodore W. ; Stefanek, Michael Edward ; Thompson, Kimberly M. / Genetic testing for lung cancer risk : If physicians can do it, should they?. In: Journal of General Internal Medicine. 2002 ; Vol. 17, No. 12. pp. 946-951.
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