Get Ready to Wnt: Prepatterning in Neuromuscular Junction Formation

Bin Zhang, Wen C. Xiong, Lin Mei

Research output: Contribution to journalShort survey

4 Scopus citations

Abstract

Clustering of acetylcholine receptors (AChR) in muscle fibers prior to innervation by motor neurons is thought to be involved in neuromuscular junction formation. Jing et al. now report in Neuron that this prepatterning of AChRs, via a novel MuSK-dependent Wnt pathway, may guide motor axons to the central region of muscle fibers for synapse formation in zebrafish.

Original languageEnglish (US)
Pages (from-to)325-327
Number of pages3
JournalDevelopmental Cell
Volume16
Issue number3
DOIs
StatePublished - Mar 17 2009

ASJC Scopus subject areas

  • Molecular Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Developmental Biology
  • Cell Biology

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