Get Ready to Wnt

Prepatterning in Neuromuscular Junction Formation

Bin Zhang, Wencheng Xiong, Lin Mei

Research output: Contribution to journalShort survey

4 Citations (Scopus)

Abstract

Clustering of acetylcholine receptors (AChR) in muscle fibers prior to innervation by motor neurons is thought to be involved in neuromuscular junction formation. Jing et al. now report in Neuron that this prepatterning of AChRs, via a novel MuSK-dependent Wnt pathway, may guide motor axons to the central region of muscle fibers for synapse formation in zebrafish.

Original languageEnglish (US)
Pages (from-to)325-327
Number of pages3
JournalDevelopmental Cell
Volume16
Issue number3
DOIs
StatePublished - Mar 17 2009

Fingerprint

Neuromuscular Junction
Neurons
Muscle
Muscles
Wnt Signaling Pathway
Fibers
Motor Neurons
Cholinergic Receptors
Zebrafish
Synapses
Cluster Analysis
Axons

ASJC Scopus subject areas

  • Developmental Biology

Cite this

Get Ready to Wnt : Prepatterning in Neuromuscular Junction Formation. / Zhang, Bin; Xiong, Wencheng; Mei, Lin.

In: Developmental Cell, Vol. 16, No. 3, 17.03.2009, p. 325-327.

Research output: Contribution to journalShort survey

Zhang, Bin ; Xiong, Wencheng ; Mei, Lin. / Get Ready to Wnt : Prepatterning in Neuromuscular Junction Formation. In: Developmental Cell. 2009 ; Vol. 16, No. 3. pp. 325-327.
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