Hb J-Antakya or α2β265(E9)Lys → Met in a Turkish family and Hb Complutense or α2β2127(H5)Gln → Glu in a Spanish family; correction of a previously published identification

Titus H.J. Huisman, Jerry B. Wilson, Abdullah Kutlar, Ke gong Yang, Song sen Chen, Brooke B. Webber, Cigdem Altay, Ana Villegas Martinez

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Almost 10 years ago we reported in this journal the characterization of Hb Hacettepe or α2β2127(H5)Gln → Glu. Unfortunately, we have to conclude that the original characterization of this Turkish variant was in error. The corrected data are presented in this short communication. The variant (α2β265(E9)Lys → Met) was (re)named Hb J-Antakya, after the city where the family resides. An abnormal Hb, observed in a Spanish family and named Hb Complutense, had the β127 Gln → Glu substitution, erroneously assigned to the Turkish variant.

Original languageEnglish (US)
Pages (from-to)229-231
Number of pages3
JournalBiochimica et Biophysica Acta (BBA)/Protein Structure and Molecular
Volume871
Issue number2
DOIs
StatePublished - Jun 5 1986

Fingerprint

Substitution reactions
Communication
hemoglobin Complutense
hemoglobin J Antakya

Keywords

  • (Human hemoglobin)
  • Amino acid substitution
  • Hb Complutense
  • Hb Hacettepe
  • Hb J-Antakya
  • Hemoglobin variant

ASJC Scopus subject areas

  • Structural Biology
  • Biophysics
  • Biochemistry
  • Molecular Biology

Cite this

Hb J-Antakya or α2β265(E9)Lys → Met in a Turkish family and Hb Complutense or α2β2127(H5)Gln → Glu in a Spanish family; correction of a previously published identification. / Huisman, Titus H.J.; Wilson, Jerry B.; Kutlar, Abdullah; Yang, Ke gong; Chen, Song sen; Webber, Brooke B.; Altay, Cigdem; Martinez, Ana Villegas.

In: Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular, Vol. 871, No. 2, 05.06.1986, p. 229-231.

Research output: Contribution to journalArticle

Huisman, Titus H.J. ; Wilson, Jerry B. ; Kutlar, Abdullah ; Yang, Ke gong ; Chen, Song sen ; Webber, Brooke B. ; Altay, Cigdem ; Martinez, Ana Villegas. / Hb J-Antakya or α2β265(E9)Lys → Met in a Turkish family and Hb Complutense or α2β2127(H5)Gln → Glu in a Spanish family; correction of a previously published identification. In: Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular. 1986 ; Vol. 871, No. 2. pp. 229-231.
@article{f50df6312d9e43df97b13b6d4355ad83,
title = "Hb J-Antakya or α2β265(E9)Lys → Met in a Turkish family and Hb Complutense or α2β2127(H5)Gln → Glu in a Spanish family; correction of a previously published identification",
abstract = "Almost 10 years ago we reported in this journal the characterization of Hb Hacettepe or α2β2127(H5)Gln → Glu. Unfortunately, we have to conclude that the original characterization of this Turkish variant was in error. The corrected data are presented in this short communication. The variant (α2β265(E9)Lys → Met) was (re)named Hb J-Antakya, after the city where the family resides. An abnormal Hb, observed in a Spanish family and named Hb Complutense, had the β127 Gln → Glu substitution, erroneously assigned to the Turkish variant.",
keywords = "(Human hemoglobin), Amino acid substitution, Hb Complutense, Hb Hacettepe, Hb J-Antakya, Hemoglobin variant",
author = "Huisman, {Titus H.J.} and Wilson, {Jerry B.} and Abdullah Kutlar and Yang, {Ke gong} and Chen, {Song sen} and Webber, {Brooke B.} and Cigdem Altay and Martinez, {Ana Villegas}",
year = "1986",
month = "6",
day = "5",
doi = "10.1016/0167-4838(86)90178-0",
language = "English (US)",
volume = "871",
pages = "229--231",
journal = "Biochimica et Biophysica Acta - Proteins and Proteomics",
issn = "1570-9639",
publisher = "Elsevier",
number = "2",

}

TY - JOUR

T1 - Hb J-Antakya or α2β265(E9)Lys → Met in a Turkish family and Hb Complutense or α2β2127(H5)Gln → Glu in a Spanish family; correction of a previously published identification

AU - Huisman, Titus H.J.

AU - Wilson, Jerry B.

AU - Kutlar, Abdullah

AU - Yang, Ke gong

AU - Chen, Song sen

AU - Webber, Brooke B.

AU - Altay, Cigdem

AU - Martinez, Ana Villegas

PY - 1986/6/5

Y1 - 1986/6/5

N2 - Almost 10 years ago we reported in this journal the characterization of Hb Hacettepe or α2β2127(H5)Gln → Glu. Unfortunately, we have to conclude that the original characterization of this Turkish variant was in error. The corrected data are presented in this short communication. The variant (α2β265(E9)Lys → Met) was (re)named Hb J-Antakya, after the city where the family resides. An abnormal Hb, observed in a Spanish family and named Hb Complutense, had the β127 Gln → Glu substitution, erroneously assigned to the Turkish variant.

AB - Almost 10 years ago we reported in this journal the characterization of Hb Hacettepe or α2β2127(H5)Gln → Glu. Unfortunately, we have to conclude that the original characterization of this Turkish variant was in error. The corrected data are presented in this short communication. The variant (α2β265(E9)Lys → Met) was (re)named Hb J-Antakya, after the city where the family resides. An abnormal Hb, observed in a Spanish family and named Hb Complutense, had the β127 Gln → Glu substitution, erroneously assigned to the Turkish variant.

KW - (Human hemoglobin)

KW - Amino acid substitution

KW - Hb Complutense

KW - Hb Hacettepe

KW - Hb J-Antakya

KW - Hemoglobin variant

UR - http://www.scopus.com/inward/record.url?scp=0022518111&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022518111&partnerID=8YFLogxK

U2 - 10.1016/0167-4838(86)90178-0

DO - 10.1016/0167-4838(86)90178-0

M3 - Article

C2 - 3707969

AN - SCOPUS:0022518111

VL - 871

SP - 229

EP - 231

JO - Biochimica et Biophysica Acta - Proteins and Proteomics

JF - Biochimica et Biophysica Acta - Proteins and Proteomics

SN - 1570-9639

IS - 2

ER -