Hb J-Antakya or α2β265(E9)Lys → Met in a Turkish family and Hb Complutense or α2β2127(H5)Gln → Glu in a Spanish family; correction of a previously published identification

Titus H.J. Huisman, Jerry B. Wilson, Abdullah Kutlar, Ke gong Yang, Song sen Chen, Brooke B. Webber, Cigdem Altay, Ana Villegas Martinez

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Almost 10 years ago we reported in this journal the characterization of Hb Hacettepe or α2β2127(H5)Gln → Glu. Unfortunately, we have to conclude that the original characterization of this Turkish variant was in error. The corrected data are presented in this short communication. The variant (α2β265(E9)Lys → Met) was (re)named Hb J-Antakya, after the city where the family resides. An abnormal Hb, observed in a Spanish family and named Hb Complutense, had the β127 Gln → Glu substitution, erroneously assigned to the Turkish variant.

Original languageEnglish (US)
Pages (from-to)229-231
Number of pages3
JournalBiochimica et Biophysica Acta (BBA)/Protein Structure and Molecular
Issue number2
Publication statusPublished - Jun 5 1986



  • (Human hemoglobin)
  • Amino acid substitution
  • Hb Complutense
  • Hb Hacettepe
  • Hb J-Antakya
  • Hemoglobin variant

ASJC Scopus subject areas

  • Biophysics
  • Structural Biology
  • Biochemistry
  • Molecular Biology

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